Aortic root sizing for transcatheter aortic valve implantation using a shape model parameterisation.
During a transcatheter aortic valve implantation, an axisymmetric implant is placed in an irregularly shaped aortic root. Implanting an incorrect size can cause complications such as leakage of blood alongside or through the implant. The aim of this study was to construct a method that determines th...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 57; no. 10; pp. 2081 - 2093 |
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| Autores principales: | , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139126434&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139126434 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Oct2019 vid: 57 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139126434 139126434 NLM31353427 10.1007/s11517-019-01996-x NLM31353427 139126434 ppf: 2081 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Aortic root sizing for transcatheter aortic valve implantation using a shape model parameterisation. aug: au: Bosmans, Bart Huysmans, Toon Lopes, Patricia Verhoelst, Eva Dezutter, Tim de Jaegere, Peter Sijbers, Jan Vander Sloten, Jos Bosmans, Johan affil: KULeuven, Faculty of Engineering Science, Departement of Mechanical Engineering, Biomechanics Section, Celestijnenlaan 300C, 3001, Leuven, Belgium sug: subj: Models, Biological Aortic Valve Surgery Algorithms Heart Valve Prosthesis Reproducibility of Results Male Tomography, X-Ray Computed Aortic Valve Female Aged, 80 and Over Heart Ventricle Computer Simulation Factor Analysis Aged, 80 & over Male Female ab: During a transcatheter aortic valve implantation, an axisymmetric implant is placed in an irregularly shaped aortic root. Implanting an incorrect size can cause complications such as leakage of blood alongside or through the implant. The aim of this study was to construct a method that determines the optimal size of the implant based on the three-dimensional shape of the aortic root. Based on the pre-interventional computed tomography scan of 89 patients, a statistical shape model of their aortic root was constructed. The weights associated with the principal components and the volume of calcification in the aortic valve were used as parameters in a classification algorithm. The classification algorithm was trained using the patients with no or mild leakage after their intervention. Subsequently, the algorithms were applied to the patients with moderate to severe leakage. Cross validation showed that a random forest classifier assigned the same size in 65 ± 7% of the training cases, while 57 ± 8% of the patients with moderate to severe leakage were assigned a different size. This initial study showed that this semi-automatic method has the potential to correctly assign an implant size. Further research is required to assess whether the different size implants would improve the outcome of those patients. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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