Increased tortuosity of ACA might be associated with increased risk of ACoA aneurysm development and less aneurysm dome size: a computer-aided analysis.
Objectives: We decided to perform computer-aided analysis of the anterior cerebral artery (ACA) to check for a potential correlation with anterior communicating artery (ACoA) aneurysm presence and growth.Methods: We retrospectively analyzed the ACA anatomy of 121 patients with ACoA aneurysms along w...
| Published in: | European Radiology Vol. 29; no. 11; pp. 6309 - 6319 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Nov2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139163642&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139163642 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2019 vid: 29 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139163642 139163642 143952856 NLM30989348 10.1007/s00330-019-06146-3 NLM30989348 139163642 ppf: 6309 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Increased tortuosity of ACA might be associated with increased risk of ACoA aneurysm development and less aneurysm dome size: a computer-aided analysis. aug: au: Krzyżewski, Roger M. Kliś, Kornelia M. Kwinta, Borys M. Gackowska, Małgorzata Gąsowski, Jerzy affil: Department of Neurosurgery and Neurotraumatology, Jagiellonian University Medical College, Botaniczna 3 Street, 31-503, Kraków, Poland sug: subj: Cerebral Aneurysm Pathology Anterior Cerebral Artery Anatomy and Histology Adult Risk Factors Retrospective Design Cerebral Angiography Methods Aged Algorithms Female Cerebral Aneurysm Middle Age Case Control Studies Angiography, Digital Subtraction Methods Anterior Cerebral Artery Male Logistic Regression Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objectives: We decided to perform computer-aided analysis of the anterior cerebral artery (ACA) to check for a potential correlation with anterior communicating artery (ACoA) aneurysm presence and growth.Methods: We retrospectively analyzed the ACA anatomy of 121 patients with ACoA aneurysms along with 121 age, risk factors, and vessel side-matched control patients without an ACoA aneurysm. We obtained their medical history and digital subtraction angiography (DSA) data from their medical records. For each patient's DSA, we extracted curve representing the course of their ACA and calculated its relative length (RL), sum of angle metrics (SOAM), triangular index (TI), product of angle distance (PAD), and inflection count metrics (ICM).Results: Patients with ACoA aneurysm had significantly higher RL (0.64 ± 0.23 vs. 0.56 ± 0.22; p < 0.01), SOAM (0.27 ± 0.19 vs. 0.18 ± 0.15; p < 0.01), PAD (0.12 ± 0.13 vs. 0.09 ± 0.11; p = 0.02), and TI (0.57 ± 0.14 vs. 0.44 ± 0.15; p < 0.01). In multivariate logistic regression analysis, after adjustment for possible confounders, SOAM (OR, 1.34; 95% CI, 1.12-1.63; p < 0.01) and TI (OR, 1.84; 95% CI, 1.47-2.35; p < 0.01) remained independently associated with higher risk of ACoA aneurysm. Additionally, we found significant negative correlations between TI and aneurysm dome size (R = - 0.194; p = 0.047).Conclusions: Increased tortuosity of ACA might increase the risk of ACoA aneurysm development and decrease the risk of aneurysm growth.Key Points: • Anterior cerebral artery's sum of angle metrics is associated with hypertension as well as with history of ischemic stroke and myocardial infarction. • Increased tortuosity of anterior cerebral artery might be associated with anterior communicating artery aneurysm development. • Tortuosity of anterior cerebral artery is negatively correlated with anterior communicating artery aneurysm dome size. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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