Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression.

Objectives: Murine models of interleukin (IL)-23-driven spondyloarthritis (SpA) have demonstrated entheseal accumulation of γδT-cells which were responsible for the majority of local IL-17A production. However, IL-23 blockers are ineffective in axial inflammation in man. This study investigated γδT-...

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Bibliographic Details

Published in:	Annals of the Rheumatic Diseases Vol. 78; no. 11; pp. 1559 - 1566
Main Authors:	Cuthbert, Richard James, Watad, Abdulla, Fragkakis, Evangelos M., Dunsmuir, Robert, Loughenbury, Peter, Khan, Almas, Millner, Peter A., Davison, Adam, Marzo-Ortega, Helena, Newton, Darren, Bridgewood, Charlie, McGonagle, Dennis G.
Format:	research Journal Article
Published:	Elsevier B.V. Nov2019
Online Access:	View this record in EBSCOhost