Salivary Gland FNA Diagnostics in a Real-Life Setting: One-Year-Experiences of the Implementation of the Milan System in a Tertiary Care Center.

The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was introduced in 2018 following other organ specific cytopathological reporting systems and it aimed at bringing a practical, evidence-based, user-friendly classification system with characterization and management algorithms. At...

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Publicado en:Cancers Vol. 11; no. 10; pp. 1589 - 1590
Autores principales: Tommola, Erkka, Tommola, Satu, Porre, Sinikka, Kholová, Ivana
Formato: research tables/charts Journal Article
Publicado: MDPI Oct2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2019
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      pub: MDPI
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        atl: Salivary Gland FNA Diagnostics in a Real-Life Setting: One-Year-Experiences of the Implementation of the Milan System in a Tertiary Care Center.
      aug:
        au:
          Tommola, Erkka
          Tommola, Satu
          Porre, Sinikka
          Kholová, Ivana
        affil: Department of Pathology, Fimlab Laboratories, Tampere University Hospital, 335 20 Tampere, Finland
      sug:
        subj:
          Salivary Gland Neoplasms Diagnosis
          Biopsy, Needle Methods
          Cytodiagnosis Methods
          Neoplasm Staging Methods
          Human
          Descriptive Statistics
          Salivary Gland Neoplasms Pathology
      ab: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was introduced in 2018 following other organ specific cytopathological reporting systems and it aimed at bringing a practical, evidence-based, user-friendly classification system with characterization and management algorithms. At the Department of Pathology, Fimlab Laboratories, Tampere, Finland all salivary fine needle aspirations (FNAs) have been given cytopathological diagnoses according to the MSRSGC since January 2018. Analyses of a one-year-period (January 2018–December 2018) consisted of 183 salivary FNA samples from 138 patients with correlation to histopathology in 90 cases with surgical follow-up. The MSRSGC performance in patient based analysis was as follows: accuracy was 90.9%, sensitivity was 61.5%, specificity was 100%, positive predictive value was 100%, and negative predictive value was 89.4%, respectively. Risks of malignancy (ROMs) in MSRSGC categories were: 0.0% (0/15) in non-diagnostic category, 100.0% (1/1) in non-neoplastic category biased by only one falsely-negative lymphoma case, 14.3% (1/7) in atypia of undetermined significance category, 0.0% (0/28) in benign neoplasm category, 27.3% (3/11) in neoplasm of uncertain malignant potential category, and 100% for both suspicious for malignancy (4/4) and malignancy (4/4) categories, respectively. The MSRSGC has been proven as a reliable classification system in salivary gland FNA routine diagnostics in a tertiary care center.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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