Alcohol consumption increases susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis.

Alcohol use in persons living with HIV (PLWH) worsens the severity of bacterial pneumonia. However, the exact mechanism(s) by which this occurs remain ill-defined. We hypothesized that alcohol in the setting of HIV infection decreases Streptococcus pneumoniae clearance from the lung through mechanis...

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Bibliographic Details

Published in:	Alcohol Vol. 80; pp. 33 - 44
Main Authors:	Samuelson, Derrick R., Siggins, Robert W., Ruan, Sanbao, Amedee, Angela M., Sun, Jiusong, Zhu, Quan Karen, Marasco, Wayne A., Taylor, Christopher M., Luo, Meng, Welsh, David A., Shellito, Judd E.
Format:	Journal Article
Published:	Elsevier B.V. Nov2019
Online Access:	View this record in EBSCOhost