Echocardiographic reference ranges for myocardial work in healthy subjects: A preliminary study.

Background: Myocardial work (MW) estimation by pressure‐strain loops (PSL) allows the non‐invasive assessment of myocardial performance. Aim of this study is to provide the reference values for global myocardial work index (WI), constructive work (CW), wasted work (WW), and work efficiency (WE) in a...

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Publicado en:Echocardiography Vol. 36; no. 10; pp. 1814 - 1825
Autores principales: Galli, Elena, John‐Matthwes, Beatrice, Rousseau, Chloé, Schnell, Frederic, Leclercq, Christophe, Donal, Erwan
Formato: diagnostic images glossary pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2019
      vid: 36
      iid: 10
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.14494
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        atl: Echocardiographic reference ranges for myocardial work in healthy subjects: A preliminary study.
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        au:
          Galli, Elena
          John‐Matthwes, Beatrice
          Rousseau, Chloé
          Schnell, Frederic
          Leclercq, Christophe
          Donal, Erwan
        affil: University of Rennes, CHU Rennes, Inserm, LTSI – UMR 1099, Rennes France
      sug:
        subj:
          Echocardiography Methods
          Myocardium Ultrasonography
          Myocardium Physiology
          Volunteer Workers
          Young Adult
          Adult
          Middle Age
          Aged
          Male
          Female
          Descriptive Statistics
          Sex Factors
          Diagnostic Tests, Routine Methods
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Myocardial work (MW) estimation by pressure‐strain loops (PSL) allows the non‐invasive assessment of myocardial performance. Aim of this study is to provide the reference values for global myocardial work index (WI), constructive work (CW), wasted work (WW), and work efficiency (WE) in a group of healthy volunteers accounting for age and gender. Methods and results: 2D standard and speckle‐tracking echocardiography were performed in 115 healthy volunteers (median age 36.3 [18–69] years, males: 67%). PSLs were used to assess MW. Mean ± standard deviation or median and inter‐quartile range, 5° and 95° percentile values for global myocardial WI, CW, WW, and WE in the whole population were 1926 ± 247 mm Hg, (1534–2356); 2224 ± 229 mm Hg, (1894–2647); 90 (61–123) mm Hg%, (38–195); and 96 (94–97)%, (91–98), respectively. Global WI (2031 ± 247 vs 1874 ± 232 mm Hg%, P = .001) and global CW (2289 ± 261 vs 2194 ± 207 mm Hg%, P = .04) were higher in women than in men. Age did not affect MW parameters. The segmental analysis showed that myocardial WI, CW, and WE were lower in the left ventricular basal segments than in the apex. The apex‐to‐base gradient was inverted for WW (all P < .0001). Conclusions: The assessment of MW is feasible in normal subjects. The presented referral ranges of global myocardial WI, CW, WW, and WE were not affected by age. An apex‐to‐base gradient was observed for all MW parameters. Nevertheless, the wide variability of MW parameters prevents for the moment the application of this technique in the routine clinical setting.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        glossary
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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