Hypoplasia of the sphenoid sinuses as a diagnostic tool in cystic fibrosis.
Purpose: To measure and compare the size of the sphenoid sinuses in patients with cystic fibrosis (CF) to patients with inflammatory sinonasal disease, and to correlate the size with number of CF mutations in each patient.Material and Methods: Ninety-six CF patients aged 5-47 years (median 19 years)...
| Publicado en: | Acta Radiologica Vol. 40; no. 5; pp. 479 - 486 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Sage Publications Inc.
Sep1999
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139329630&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139329630 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02841851 1XG jtl: Acta Radiologica issn: 02841851 maglogo: Y pubinfo: dt: Sep1999 vid: 40 iid: 5 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 139329630 139329630 NLM10485235 139329630 10.3109/02841859909175571 NLM10485235 139329630 ppf: 479 ppct: 7 formats: tig: atl: Hypoplasia of the sphenoid sinuses as a diagnostic tool in cystic fibrosis. aug: au: Eggesbø, H B Eken, T Eiklid, K Kolmannskog, F affil: Department of Radiology, Aker Hospital, University of Oslo, Norway sug: subj: Paranasal Sinus Diseases Sphenoid Sinus Abnormalities Tomography, X-Ray Computed Cystic Fibrosis Blood Proteins Diagnosis, Differential Human Child, Preschool Child Middle Age Paranasal Sinus Diseases Complications Cystic Fibrosis Complications Mutation Adult Membrane Proteins Male Adolescence Sphenoid Sinus Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Child, Preschool: 2-5 years Child: 6-12 years Middle Aged: 45-64 years Adult: 19-44 years Adolescent: 13-18 years Male Female ab: Purpose: To measure and compare the size of the sphenoid sinuses in patients with cystic fibrosis (CF) to patients with inflammatory sinonasal disease, and to correlate the size with number of CF mutations in each patient.Material and Methods: Ninety-six CF patients aged 5-47 years (median 19 years) and 130 control patients aged 7-51 years (median 32 years) were examined using coronal CT of the paranasal sinuses. In each patient, the CT image with the largest coronal area of the sphenoid sinuses was scanned into a Macintosh computer with image processing and analysis software. Largest coronal area and largest circumference of the right and left sphenoid sinuses were automatically measured. Additionally, antero-posterior extension of the sphenoid sinuses was calculated from the lateral scanograms. CF patients were grouped according to number of confirmed mutations (CF-0, CF-1, or CF-2).Results: CF patients generally had small sphenoid sinuses. The largest differences for all parameters were observed between the CF-2 and the control groups (p<0.0001). No CF-2 patient had pneumatization beyond the presphenoid. The CF-0 and CF-1 groups consisted of two populations, one overlapping the CF-2 group and another overlapping the control group.Conclusion: Hypoplasia of the sphenoid sinuses is a characteristic finding in CF patients. When pneumatization of the basisphenoid is present, the existing CF diagnosis should be questioned. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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