Diagnostic accuracy of diffusion tensor imaging in differentiating malignant from benign compressed vertebrae.
Purpose: To study diagnostic accuracy of diffusion tensor imaging (DTI) in differentiating malignant from benign compressed vertebrae. Methods: This study was done on 43 patients with compressed vertebrae on conventional magnetic resonance study that underwent DTI. The mean diffusivity (MD) and frac...
| Publicado en: | Neuroradiology Vol. 61; no. 11; pp. 1291 - 1297 |
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| Autores principales: | , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Nov2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139365884&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139365884 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Nov2019 vid: 61 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139365884 139365884 139365884 10.1007/s00234-019-02286-x 139365884 ppf: 1291 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Diagnostic accuracy of diffusion tensor imaging in differentiating malignant from benign compressed vertebrae. aug: au: Razek, Ahmed Abdel Khalek Abdel Sherif, Fatma Mohamed affil: Department of Diagnostic Radiology, Mansoura Faculty of Medicine, 13551, Mansoura, Egypt sug: subj: Magnetic Resonance Imaging Methods Cervical Vertebrae Pathology Lumbar Vertebrae Pathology Thoracic Vertebrae Pathology Spinal Neoplasms Diagnosis Diagnosis, Differential Sensitivity and Specificity Human Noninvasive Procedures Interrater Reliability ab: Purpose: To study diagnostic accuracy of diffusion tensor imaging (DTI) in differentiating malignant from benign compressed vertebrae. Methods: This study was done on 43 patients with compressed vertebrae on conventional magnetic resonance study that underwent DTI. The mean diffusivity (MD) and fractional anisotropy (FA) of malignant (n = 24) and benign (n = 19) compressed vertebrae were calculated by two readers. Results: There was a significantly lower (P = 0.001) MD of both readers between malignant (0.74 ± 0.2 and 0.78 ± 0.2 × 10−3 mm2/s) and benign (1.67 + 0.3 and 1.63 ± 0.3 × 10−3 mm2/s) compressed vertebrae. The FA of malignant compressed vertebrae of both readers (0.55 ± 0.2 and 0.52 ± 0.1) was significantly higher (P = 0.001) than that of benign (0.26 ± 0.1 and 0.28 ± 0.1) compressed vertebrae. There was excellent inter-reader agreement between both readers using MD (K = 0.91) and FA (K = 0.86). The thresholds of MD and FA used for differentiating malignant from benign compressed vertebrae of both readers were 1.15 and 1.16 × 10−3 mm2/s and 0.37 and 0.34 with area under the curve (AUC) of 0.98, 0.96, 0.93, and 0.92 and diagnostic accuracy of 95.3%, 88.4%, 90.1%, and 86.0% respectively. Combined MD and FA revealed AUC of 0.99 and 0.97 and diagnostic accuracy of 95.3% and 93.0% by both readers respectively. Conclusion: DTI is a non-invasive technique providing accurate imaging parameters that can be used for differentiating malignant from benign compressed vertebrae. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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