Determinate root development in the halted primary root1 mutant of Arabidopsis correlates with death of root initial cells and an enhanced auxin response.

The transit from indeterminate to determinate root developmental program compromises growth and causes the differentiation of the meristem, but a direct link between this process with auxin signaling and/or viability of initial cells remains untested. Here, through the isolation and characterization...

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Publicado en:Protoplasma Vol. 256; no. 6; pp. 1657 - 1667
Autores principales: Raya-González, Javier, Ortiz-Castro, Randy, López-Bucio, José
Formato: Journal Article
Publicado: Springer Nature Nov2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2019
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00709-019-01409-8
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        atl: Determinate root development in the halted primary root1 mutant of Arabidopsis correlates with death of root initial cells and an enhanced auxin response.
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          Raya-González, Javier
          Ortiz-Castro, Randy
          López-Bucio, José
        affil: Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Edificio A1', Ciudad Universitaria, C. P., 58030, Morelia, Michoacán, Mexico
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      ab: The transit from indeterminate to determinate root developmental program compromises growth and causes the differentiation of the meristem, but a direct link between this process with auxin signaling and/or viability of initial cells remains untested. Here, through the isolation and characterization of the halted primary root1 (hpr1) mutant of Arabidopsis, which develops primary and lateral roots with genetically stable determinate growth after germination, we show that the differentiation of the root meristem correlates with enhanced auxin responsiveness and is preceded by the death of provasculature initial cells in both primary and lateral roots. Supplementation of indole-3-acetic acid causes both a dose-dependent repression of primary root growth and an induction of DR5:uidA expression in wild-type seedlings, and these effects were exacerbated in hpr1 mutants. The damage of provasculature initial cells in the root of hpr1 mutants occurred at earlier times than the full differentiation of the meristem, and correlates with a reduced expression domain of CycB1:uidA and PRZ:uidA. Thus, HPR1 plays critical functions for stem cell maintenance, auxin homeostasis, cell division in the meristem, and indeterminate root growth.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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