Local clinical diagnostic reference levels for chest and abdomen CT examinations in adults as a function of body mass index and clinical indication: a prospective multicenter study.

Objectives: To compare institutional dose levels based on clinical indication and BMI class to anatomy-based national DRLs (NDRLs) in chest and abdomen CT examinations and to assess local clinical diagnostic reference levels (LCDRLs).Methods: From February 2017 to June 2018, after protocol optimizat...

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Publicado en:European Radiology Vol. 29; no. 12; pp. 6794 - 6805
Autores principales: Brat, Hugues, Zanca, Federica, Montandon, Stéphane, Racine, Damien, Rizk, Benoit, Meicher, Eric, Fournier, Dominique
Formato: research Journal Article
Publicado: Springer Nature Dec2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2019
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-019-06257-x
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        atl: Local clinical diagnostic reference levels for chest and abdomen CT examinations in adults as a function of body mass index and clinical indication: a prospective multicenter study.
      aug:
        au:
          Brat, Hugues
          Zanca, Federica
          Montandon, Stéphane
          Racine, Damien
          Rizk, Benoit
          Meicher, Eric
          Fournier, Dominique
        affil: Institut de Radiologie de Sion, Groupe 3R, Sion, Switzerland
      sug:
        subj:
          Radiography, Abdominal Methods
          Radiation Dosage
          Body Mass Index
          Radiography, Thoracic Methods
          Tomography, X-Ray Computed Methods
          Human
          Adolescence
          Adult
          Reference Values
          Prospective Studies
          Aged, 80 and Over
          Thorax
          Middle Age
          Young Adult
          Physical Examination
          Aged
          Male
          Female
          Abdomen
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Scales
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Objectives: To compare institutional dose levels based on clinical indication and BMI class to anatomy-based national DRLs (NDRLs) in chest and abdomen CT examinations and to assess local clinical diagnostic reference levels (LCDRLs).Methods: From February 2017 to June 2018, after protocol optimization according to clinical indication and body mass index (BMI) class (< 25; ≥ 25), 5310 abdomen and 1058 chest CT series were collected from 5 CT scanners in a Swiss multicenter group. Clinical indication-based institutional dose levels were compared to the Swiss anatomy-based NDRLs. Statistical significance was assessed (p < 0.05). LCDRLs were calculated as the third quartile of the median dose values for each CT scanner.Results: For chest examinations, dose metrics based on clinical indication were always below P75 NDRL for CTDIvol (range 3.9-6.4 vs. 7.0 mGy) and DLP (164.0-211.2 vs. 250 mGycm) in all BMI classes except for DLP in BMI ≥ 25 (248.8-255.4 vs. 250.0 mGycm). For abdomen examinations, they were significantly lower or not different than P50 NDRLs for all BMI classes (3.8-9.0 vs. 10.0 mGy and 192.9-446.8 vs. 470mGycm). The estimated LCDRLs show a drop in CTDIvol (21% for chest and 32% for abdomen, on average) with respect to current DRLs. When considering BMI stratification, the largest LCDRL difference within the same clinical indication is for renal tumor (4.6 mGy for BMI < 25 vs. 10.0 mGy for BMI ≥ 25; - 117%).Conclusion: The results suggest the necessity of estimating clinical indication-based DRLs, especially for abdomen examinations. Stratifying per BMI class allows further optimization of the CT doses.Key Points: • Our data show that clinical indication-based DRLs might be more appropriate than anatomy-based DRLs and might help in reducing large variations in dose levels for the same type of examinations. • Stratifying the data per patient-size subgroups (non-overweight, overweight) allows a better optimization of CT doses and therefore the possibility to set LCDRLs based on BMI class. • Institutions who are fostering continuous dose optimization and LDRLs should consider defining protocols based on clinical indication and BMI group, to achieve ALARA.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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