Comparison of meperidine, tramadol and fentanyl for post‐spinal shivering prevention during cesarean delivery: A double‐blind randomized controlled trial.
Aim: To assess the effects of intravenously administered meperidine, fentanyl and tramadol in reducing the incidence, onset time and severity of the shivering response in parturients during cesarean delivery under spinal anesthesia. Secondary outcomes included patient satisfaction and sedation score...
| Publicado en: | Journal of Obstetrics & Gynaecology Research Vol. 45; no. 11; pp. 2202 - 2209 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Wiley-Blackwell
Nov2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139502444&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139502444 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13418076 Q17 jtl: Journal of Obstetrics & Gynaecology Research issn: 13418076 maglogo: Y pubinfo: dt: Nov2019 vid: 45 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 139502444 139502444 139502444 10.1111/jog.14106 139502444 ppf: 2202 ppct: 7 formats: tig: atl: Comparison of meperidine, tramadol and fentanyl for post‐spinal shivering prevention during cesarean delivery: A double‐blind randomized controlled trial. aug: au: Jayaraj, Ashokkumar Balachander, Hemavathi Kuppusamy, Suresh K. Arusamy, Sivakumar Rai, Yeshith Siddiqui, Naveed affil: Department of Anesthesia and Pain Management, Mount Sinai Hospital, Toronto Ontario, Canada sug: subj: Meperidine Administration and Dosage Tramadol Administration and Dosage Fentanyl Administration and Dosage Shivering In Pregnancy Anesthesia, Spinal Adverse Effects Cesarean Section Administration, Intravenous Human Patient Satisfaction Randomized Controlled Trials Random Assignment Treatment Outcomes Pregnancy Female Double-Blind Studies Expectant Mothers Adult Comparative Studies Adult: 19-44 years Female ab: Aim: To assess the effects of intravenously administered meperidine, fentanyl and tramadol in reducing the incidence, onset time and severity of the shivering response in parturients during cesarean delivery under spinal anesthesia. Secondary outcomes included patient satisfaction and sedation scores. Methods: After Ethics board approval and informed written consent, 350 parturients (ASA physical status I or II), between 20 and 40 years of age, undergoing emergency or elective cesarean delivery under spinal anesthesia were recruited. Parturients were then randomly allocated to seven study groups: normal saline (control), low‐dose meperidine (0.5 mg/kg), high‐dose meperidine (0.75 mg/kg), low‐dose fentanyl (0.5 mcg/kg), high‐dose fentanyl (0.75 mcg/kg), low‐dose tramadol (0.5 mg/kg) and high‐dose tramadol (0.75 mg/kg). The incidence, onset time and severity of shivering, along with patient satisfaction and sedation scores were measured. Results: All study drugs showed significant reduction in incidence, onset time and severity of shivering and greater satisfaction scores compared to the control group (P < 0.01). Within each drug class, no significant differences in shivering were found between the high‐dose and low‐dose groups. Among study drugs, low‐dose tramadol was superior due to shivering prevention and significantly reduced sedation. Conclusion: Intravenously administered meperidine, fentanyl and tramadol reduce shivering incidence, onset time and severity in parturients undergoing cesarean delivery following spinal anesthesia. Importantly, low‐dose intravenous tramadol (0.5 mg/kg) allowed shivering prevention and low sedation scores, thereby offering greater parturient satisfaction and better maternal–newborn bonding. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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