Effects of Overweight or Obesity on Brain Resting State Functional Connectivity of Children with Autism Spectrum Disorder.
Evidence on neurophysiological correlates of coexisting autism spectrum disorders (ASD) and overweight/obesity may elucidate mechanisms leading to the observed greater risk of obesity in children with ASD. An exploratory secondary data analysis was performed on resting state functional magnetic reso...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 49; no. 12; pp. 4751 - 4761 |
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| Autores principales: | , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139567971&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139567971 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Dec2019 vid: 49 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139567971 139567971 139567971 10.1007/s10803-019-04187-7 139567971 ppf: 4751 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Effects of Overweight or Obesity on Brain Resting State Functional Connectivity of Children with Autism Spectrum Disorder. aug: au: Kahathuduwa, Chanaka N. West, Blake Mastergeorge, Ann affil: Department of Human Development and Family Studies, College of Human Sciences, Texas Tech University, Box 1230, 1301 Akron Street, 79409-1230, Lubbock, TX, USA sug: subj: Pediatric Obesity Risk Factors Brain Mapping Methods Autism Spectrum Disorder Complications Magnetic Resonance Imaging Methods Autism Spectrum Disorder Diagnosis Child Health Human Exploratory Research Secondary Analysis Neurophysiology Child Child: 6-12 years ab: Evidence on neurophysiological correlates of coexisting autism spectrum disorders (ASD) and overweight/obesity may elucidate mechanisms leading to the observed greater risk of obesity in children with ASD. An exploratory secondary data analysis was performed on resting state functional magnetic resonance imaging (rs-fMRI) data of children downloaded from the ABIDE Preprocessed database (n = 81). Children with isolated ASD showed hypo-connectivity between anterior and posterior default mode network (DMN) (p = 0.003; FWER). Children with coexisting ASD and overweight/obesity showed hyper-connectivity between anterior and posterior DMN (p = 0.015; FWER). More evidence is needed to confirm these contrasting rs-fMRI connectivity profiles and to explicate causal inferences regarding neurophysiological mechanisms associated with coexisting ASD and overweight/obesity. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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