Building Three-Dimensional Intracranial Aneurysm Models from 3D-TOF MRA: a Validation Study.

To create realistic three-dimensional (3D) vascular models from 3D time-of-flight magnetic resonance angiography (3D-TOF MRA) of an intracranial aneurysm (IA). Thirty-two IAs in 31 patients were printed using 3D-TOF MRA source images from polylactic acid (PLA) raw material. Two observers measured th...

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Publicado en:Journal of Digital Imaging Vol. 32; no. 6; pp. 963 - 971
Autores principales: Acar, Turker, Karakas, Asli Beril, Ozer, Mehmet Asim, Koc, Ali Murat, Govsa, Figen
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Dec2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2019
      vid: 32
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-019-00256-6
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        atl: Building Three-Dimensional Intracranial Aneurysm Models from 3D-TOF MRA: a Validation Study.
      aug:
        au:
          Acar, Turker
          Karakas, Asli Beril
          Ozer, Mehmet Asim
          Koc, Ali Murat
          Govsa, Figen
        affil: Department of Radiology, University of Health Sciences Bozyaka Education and Training Hospital, Izmir, Turkey
      sug:
        subj:
          Cerebral Aneurysm
          Models, Structural
          Magnetic Resonance Angiography Methods
          Imaging, Three-Dimensional
          Human
          Printing, Three-Dimensional
          Intraclass Correlation Coefficient
          Validation Studies
          Tomography, X-Ray Computed
          Wilcoxon Rank Sum Test
          Spearman's Rank Correlation Coefficient
          Algorithms
          Models, Anatomic
          Retrospective Design
          T-Tests
          Confidence Intervals
          Data Analysis Software
          Male
          Female
          Middle Age
          Aged
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: To create realistic three-dimensional (3D) vascular models from 3D time-of-flight magnetic resonance angiography (3D-TOF MRA) of an intracranial aneurysm (IA). Thirty-two IAs in 31 patients were printed using 3D-TOF MRA source images from polylactic acid (PLA) raw material. Two observers measured the maximum IA diameter at the longest width twice separately. A total mean of four measurements as well as each observer's individual average MRA lengths were calculated. After printing, 3D-printed anatomic models (PAM) underwent computed tomography (CT) acquisition and each observer measured them using the same algorithm as applied to MRA. Inter- and intra-observer consistency for the MRA and CT measurements were analyzed using the intraclass correlation coefficient (ICC) and a Bland-Altman plot. The mean maximum aneurysm diameter obtained from four MRA evaluations was 8.49 mm, whereas it was 8.83 mm according to the CT 3D PAM measurement. The Wilcoxon test revealed slightly larger mean CT 3D PAM diameters than the MRA measurements. The Spearman's correlation test yielded a positive correlation between MRA and CT lengths of 3D PAMs. Inter and intra-observer consistency were high in consecutive MRA and CT measurements. According to Bland-Altman analyses, the aneurysmal dimensions obtained from CT were higher for observer 1 and observer 2 (a mean of 0.32 mm and 0.35 mm, respectively) compared to the MRA measurements. CT dimensions were slightly overestimated compared to MRA measurements of the created models. We believe the discrepancy may be related to the Laplacian algorithm applied for surface smoothing and the high slice thickness selection that was used. However, ICC provided high consistency and reproducibility in our cohort. Therefore, it is technically possible to produce 3D intracranial aneurysm models from 3D-TOF MRA images.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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