High resolution spatio-temporal EEG-MEG analysis of rolandic spikes.

Using high resolution EEG and MEG and a realistic volume conductor model, the authors investigated spatio-temporal aspects of the sources of spikes in children with benign rolandic epilepsy. A 64-channel EEG and simultaneous 151-channel MEG of interictal spike activity in five children all having ge...

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Publicado en:Journal of Clinical Neurophysiology Vol. 21; no. 2; pp. 84 - 96
Autores principales: Huiskamp, Geertjan, van Der Meij, Wil, van Huffelen, Alexander, van Nieuwenhuizen, Onno
Formato: clinical trial research Journal Article
Publicado: Lippincott Williams & Wilkins Mar2004
Acceso en línea:Ver este registro en EBSCOhost
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      issn: 07360258
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    pubinfo:
      dt: Mar2004
      vid: 21
      iid: 2
      pid: 5086
      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        139573952
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        NLM15284598
        139573952
        10.1097/00004691-200403000-00002
        NLM15284598
        139573952
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      tig:
        atl: High resolution spatio-temporal EEG-MEG analysis of rolandic spikes.
      aug:
        au:
          Huiskamp, Geertjan
          van Der Meij, Wil
          van Huffelen, Alexander
          van Nieuwenhuizen, Onno
        affil: Department of Clinical Neurophysiology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
      sug:
        subj:
          Diagnosis, Computer Assisted Methods
          Electroencephalography Methods
          Epilepsy, Partial Diagnosis
          Epilepsy, Partial Physiopathology
          Brain Physiopathology
          Brain Mapping Methods
          Diagnosis, Neurologic Methods
          Magnetic Resonance Imaging Methods
          Brain Mapping Equipment and Supplies
          Sensitivity and Specificity
          Algorithms
          Treatment Outcomes
          Male
          Reproducibility of Results
          Computer Simulation
          Female
          Human
          Models, Biological
          Electroencephalography Equipment and Supplies
          Child, Preschool
          Child
          Clinical Trials
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Questionnaires
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Male
          Female
      ab: Using high resolution EEG and MEG and a realistic volume conductor model, the authors investigated spatio-temporal aspects of the sources of spikes in children with benign rolandic epilepsy. A 64-channel EEG and simultaneous 151-channel MEG of interictal spike activity in five children all having general and/or focal seizures were recorded. A spatio-temporal multiple signal classification (MUSIC) analysis was performed on the spike data. Sources having a complex spatio-temporal configuration as well as single stationary sources were found. Results for the EEG and MEG were different. In this group of five patients, both high resolution EEG and MEG revealed that in some cases sources well separated in space and time exist, whereas in other cases only single source activity can be resolved. For multiple sources, differences for EEG and MEG in timing and localization of activity suggest that sources are spatio-temporally distributed. Sources can propagate from initial activity in the finger/hand area around the central sulcus down to the mouth/tongue area.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        Journal Article
      ougenre: Article
    language: English
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