Impaired Neurocognitive Performance and Mortality in HIV: Assessing the Prognostic Value of the HIV-Dementia Scale.
This study examined whether global HIV-associated neurocognitive impairment (NCI), assessed with the HIV-Dementia Scale (HDS), predicted mortality in an ethnically diverse sample of 209 HIV-positive adults. Participants were predominantly in the mid-range of illness at baseline, and followed over 13...
| Publicado en: | AIDS & Behavior Vol. 23; no. 12; pp. 3482 - 3493 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139632699&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139632699 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Dec2019 vid: 23 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139632699 139632699 144156101 139632699 10.1007/s10461-019-02423-w 139632699 ppf: 3482 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Impaired Neurocognitive Performance and Mortality in HIV: Assessing the Prognostic Value of the HIV-Dementia Scale. aug: au: Banerjee, Nikhil McIntosh, Roger C. Ironson, Gail affil: Department of Psychology, University of Miami, 5665 Ponce de Leon Blvd., 33124-0751, Coral Gables, FL, USA sug: subj: HIV Infections Complications Cognition Disorders HIV Infections Mortality Risk Assessment HIV-Positive Persons Psychosocial Factors Human Adult Confidence Intervals Executive Function Attention Ethnic Groups Prospective Studies HIV Infections Physiopathology Neuropsychological Tests HIV Infections Prognosis Adult: 19-44 years ab: This study examined whether global HIV-associated neurocognitive impairment (NCI), assessed with the HIV-Dementia Scale (HDS), predicted mortality in an ethnically diverse sample of 209 HIV-positive adults. Participants were predominantly in the mid-range of illness at baseline, and followed over 13-years. At baseline, 31 (15%) participants scored in the NCI range (HDS ≤ 10); 58 (28%) died during follow-up. Baseline NCI was significantly associated with earlier mortality (HR = 2.10, 95% CI [1.10–4.00]) independent of sociodemographic and HIV disease-related covariates. Less errors on the antisaccade task, an index of executive/attention control, was the only HDS subtest predicting earlier mortality (HR = 0.72, 95% CI [0.58–0.90]). In the absence of an AIDS-defining condition, NCI, particularly in the executive/attention domain, is an independent prognostic marker of mortality in a diverse HIV-positive cohort. These findings highlight the clinical utility of brief cognitive screening measures in this population. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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