Expression of the potential therapeutic target claudin-18.2 is frequently decreased in gastric cancer: results from a large Caucasian cohort study.

Gastric cancer (GC) is frequently diagnosed and treated in advanced tumour stages with poor prognosis. Recent studies have identified isoform 2 of the tight junction protein claudin-18 (CLDN18.2) as a promising target in GC therapy. In this study, we aimed to outline the expression of CLDN18.2 and i...

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Bibliographic Details
Published in:Virchows Archiv: European Journal of Pathology Vol. 475; no. 5; pp. 563 - 572
Main Authors: Dottermusch, Matthias, Krüger, Sandra, Behrens, Hans-Michael, Halske, Christine, Röcken, Christoph
Format: pictorial research tables/charts Journal Article
Published: Springer Nature Nov2019
Online Access:View this record in EBSCOhost