Downregulating Serine Hydroxymethyltransferase 2 Deteriorates Hepatic Ischemia-Reperfusion Injury through ROS/JNK/P53 Signaling in Mice.

Background. Serine hydroxymethyltransferase 2 (SHMT2) activity ensures that cells have a survival advantage in ischemic conditions and regulates redox homeostasis. In this study, we aimed to investigate the role of SHMT2 after hepatic ischemia-reperfusion (IR), which involves hypoxia, ischemic condi...

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Detalles Bibliográficos
Publicado en:BioMed Research International pp. 1 - 10
Autores principales: Wu, Hao, Bai, He, Duan, Shigang, Yuan, Fangchao
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 11/18/2019
Acceso en línea:Ver este registro en EBSCOhost