German value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30.

Purpose: The EORTC QLU-C10D is a new multi-attribute utility instrument derived from the EORTC QLQ-C30, a widely used cancer-specific quality of life questionnaire. It covers ten dimensions: physical, role, social, emotional functioning, pain, fatigue, sleep, appetite, nausea, and bowel problems. To...

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Publicado en:Quality of Life Research Vol. 28; no. 12; pp. 3197 - 3212
Autores principales: Kemmler, Georg, Gamper, Eva, Nerich, Virginie, Norman, Richard, Viney, Rosalie, Holzner, Bernhard, King, Madeleine
Formato: Journal Article
Publicado: Springer Nature Dec2019
Acceso en línea:Ver este registro en EBSCOhost
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        atl: German value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30.
      aug:
        au:
          Kemmler, Georg
          Gamper, Eva
          Nerich, Virginie
          Norman, Richard
          Viney, Rosalie
          Holzner, Bernhard
          King, Madeleine
        affil: Division of Psychiatry I, Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University of Innsbruck, Innsbruck, Austria
      sug:
        subj:
          Quality of Life Psychosocial Factors
          Neoplasms Psychosocial Factors
          Male
          Aged, 80 and Over
          Middle Age
          Pain Psychosocial Factors
          Adult
          Adolescence
          Young Adult
          Aged
          Fatigue Psychosocial Factors
          Female
          Nausea Psychosocial Factors
          Logistic Regression
          Germany
          Questionnaires
          Aged, 80 & over
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Adolescent: 13-18 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: The EORTC QLU-C10D is a new multi-attribute utility instrument derived from the EORTC QLQ-C30, a widely used cancer-specific quality of life questionnaire. It covers ten dimensions: physical, role, social, emotional functioning, pain, fatigue, sleep, appetite, nausea, and bowel problems. To allow national health attitudes to be reflected, country-specific valuations are being performed by collaboration of the Multi-Attribute Utility Cancer (MAUCa) Consortium and the EORTC. The purpose of this paper is to provide German value sets (utility weights) for the QLU-C10D.Methods: Valuations were run in a web-based setting in two general population samples of approximately 2000 adults in total. As the German version of the QLQ-C30 is presently undergoing a revision of the wording of one response category, valuations for both the current and the new version were performed (Germany 1 and 2). Utilities were elicited using a discrete choice experiment (DCE). Data were analyzed by conditional logistic regression and mixed logits.Results: Completion rates were 88.3% (1002/1135) and 90.4% (1016/1124) for Germany 1 and Germany 2 valuations, respectively. Dimensions with the largest impact on utility weights were, in this order: physical functioning, pain, role functioning, social functioning and nausea (same ordering for both German versions). Several violations of the logical ordering of levels were observed for Germany 1; this was largely improved for Germany 2.Conclusion: This study established German utility weights for the cancer-specific utility instrument QLU-C10D.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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