Cancer survivors who fully participate in the PROFILES registry have better health-related quality of life than those who drop out.
Purpose: Attrition and subsequent missing data pose a challenge in longitudinal research in oncology. This study examined factors associated with attrition in the PROFILES registry, and its impact on observed health-related quality of life (HRQOL) estimates.Methods: Sociodemographic, clinical, and H...
| Publicado en: | Journal of Cancer Survivorship Vol. 13; no. 6; pp. 829 - 840 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139882245&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139882245 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19322259 46CU jtl: Journal of Cancer Survivorship issn: 19322259 maglogo: N pubinfo: dt: Dec2019 vid: 13 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139882245 139882245 NLM31493162 10.1007/s11764-019-00793-7 NLM31493162 139882245 ppf: 829 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Cancer survivors who fully participate in the PROFILES registry have better health-related quality of life than those who drop out. aug: au: Ramsey, Imogen de Rooij, Belle H. Mols, Floortje Corsini, Nadia Horevoorts, Nicole J. E. Eckert, Marion van de Poll-Franse, Lonneke V. affil: Rosemary Bryant AO Research Centre, School of Nursing and Midwifery and UniSA Cancer Research Institute, University of South Australia, Adelaide, Australia sug: subj: Quality of Life Psychosocial Factors Prospective Studies Aged, 80 and Over Aged Data Collection Female Male Scales Aged, 80 & over Aged: 65+ years Female Male ab: Purpose: Attrition and subsequent missing data pose a challenge in longitudinal research in oncology. This study examined factors associated with attrition in the PROFILES registry, and its impact on observed health-related quality of life (HRQOL) estimates.Methods: Sociodemographic, clinical, and HRQOL data were collected annually from a cohort of 2625 colorectal cancer survivors between 2010 and 2015. Participant characteristics according to time of dropout were compared using analysis of variance and chi-square tests. Predictors of attrition were examined in logistic regression analysis. Multilevel linear mixed models were constructed to investigate associations between attrition and HRQOL over time.Results: Participants who dropped out were more likely to be female (OR = 1.23, CI = 1.02-1.47), older (OR = 1.20, CI = 1.09-1.33), less educated (OR = 1.64, CI = 1.30-2.11), and to have depressive symptoms (OR = 1.84, CI = 1.39-2.44) than full responders, and less likely to have high socioeconomic status (OR = 0.74, CI = 0.61-0.94). Participants who dropped out earlier reported significantly worse HRQOL, functioning, and psychosocial symptoms, which declined at a steeper rate over time, than full responders.Conclusions: Cancer survivors' HRQOL may be overestimated in longitudinal research due to attrition of the most unwell participants.Implications For Cancer Survivors: Cancer survivors with the poorest health are at risk of dropping out of PROFILES and possibly withdrawing from other activities. Optimizing participation in PROFILES-a potential mechanism for providing information and access to support-is an avenue for keeping this group engaged. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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