Decision-making for pediatric allergy immunotherapy for aeroallergens: a narrative review.
There has been exciting progress in diagnosis and in the treatment of allergic patients. The objective of this review is to summarize the most relevant contributions in the past 10 years with a special focus on the pediatric population allergic to aeroallergens and provide the most relevant referenc...
| Published in: | European Journal of Pediatrics Vol. 178; no. 12; pp. 1801 - 1813 |
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| Main Authors: | , , , , , , , |
| Format: | review tables/charts Journal Article |
| Published: |
Springer Nature
Dec2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139882510&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139882510 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03406199 CR1 jtl: European Journal of Pediatrics issn: 03406199 maglogo: N pubinfo: dt: Dec2019 vid: 178 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 139882510 139882510 NLM31414212 139882510 10.1007/s00431-019-03444-2 NLM31414212 139882510 ppf: 1801 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Decision-making for pediatric allergy immunotherapy for aeroallergens: a narrative review. aug: au: Tortajada-Girbés, Miguel Mesa del Castillo, María Larramona, Helena Lucas, José Manuel Álvaro Lozano, Montserrat Tabar, Ana Isabel Soler López, Begoña Martínez-Cañavate, Ana affil: Paediatric Allergology and Pulmonology Unit, Dr. Peset University Hospital, Valencia, Spain sug: subj: Decision Making Allergens Immunology Desensitization, Immunologic Child Inhalation Exposure Child: 6-12 years ab: There has been exciting progress in diagnosis and in the treatment of allergic patients. The objective of this review is to summarize the most relevant contributions in the past 10 years with a special focus on the pediatric population allergic to aeroallergens and provide the most relevant references and practical issues for the decision-making. Current guidelines on allergy diagnosis recommend a thorough clinical history as the first step, followed by allergen extract testing using an in vivo prick test and/or an in vitro specific IgE test. Molecular diagnosis is recommended when previous tests are inconclusive. In practice, the most important factors to decide the AIT treatment are the actual intensity and duration of the patient's symptoms and the availability of appropriate AIT products for the patient's sensitization profile at high allergen concentrations and with confirmed efficacy and safety from clinical trials. This document summarizes outstanding references for allergic immunotherapy decision-making and provides summary tables and figures analyzing the most important factors related to the decision for allergen immunotherapy and the safety risks related. The experts concluded that AIT is efficacious and safe for the treatment of allergic patients that is available for the most frequent aeroallergens.What is Known:• The prevalence of allergic asthma and rhinitis in children has increased in recent decades.• The efficacy and safety of allergen immunotherapy has been shown in multiple studies and systematic reviews.What is New:• This document summarizes outstanding references for allergic immunotherapy decision-making and provides summary tables and figures analyzing the most important factors related to the decision for allergen immunotherapy and the safety risks related. Recommendations of expert authors for the decision of the patients more suitable for allergen immunotherapy are included. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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