Longitudinal trajectories of neurocognitive test performance among individuals with perinatal HIV-infection and -exposure: adolescence through young adulthood.
There are an estimated 2.1 million youth less than 15 years of age living with HIV globally (the majority perinatally HIV-infected [PHIV]) and millions more perinatally HIV-exposed uninfected (PHEU) youth who are expected to survive through adolescence and into adulthood. Transitioning from adolesce...
| Publicado en: | AIDS Care Vol. 32; no. 1; pp. 21 - 30 |
|---|---|
| Autores principales: | , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jan2020
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139899087&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 139899087 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09540121 AAE jtl: AIDS Care issn: 09540121 maglogo: N pubinfo: dt: Jan2020 vid: 32 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 139899087 139899087 139899087 10.1080/09540121.2019.1626343 139899087 ppf: 21 ppct: 9 formats: tig: atl: Longitudinal trajectories of neurocognitive test performance among individuals with perinatal HIV-infection and -exposure: adolescence through young adulthood. aug: au: Robbins, Reuben N. Zimmerman, R. Korich, R. Raymond, J. Dolezal, C. Choi, C. J. Leu, C. S. Nguyen, N. Malee, K. Wiznia, A. Abrams, E. J. Mellins, C. A. affil: HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University Medical Center, New York, NY, USA sug: subj: HIV Infections Diagnosis HIV Infections Diagnosis HIV-Positive Persons Psychosocial Factors HIV-Positive Persons Psychosocial Factors Executive Function Evaluation Neuropsychological Tests Task Performance and Analysis Human Descriptive Statistics Mental Processes Motor Skills Memory, Short Term Prospective Studies Infant Adult Adolescence Young Adult Fetus Infant: 1-23 months Adult: 19-44 years Adolescent: 13-18 years Fetus, conception to birth ab: There are an estimated 2.1 million youth less than 15 years of age living with HIV globally (the majority perinatally HIV-infected [PHIV]) and millions more perinatally HIV-exposed uninfected (PHEU) youth who are expected to survive through adolescence and into adulthood. Transitioning from adolescence to young adulthood requires adaptation to more demanding social interactions, academic pressures, and individual responsibilities which place distinct demands on neurocognitive functions. This study examined longitudinal trajectories of neurocognitive test performance in the domains of processing speed (PS), working memory (WM), and executive functioning (EF) among PHIV and demographically similar PHEU from adolescence through young adulthood. Data for this paper come from four time points, spanning approximately 10 years, within the Child and Adolescent Self-Awareness and Health Study (CASAH). Youth age ranged from 15 to 29 years. Longitudinal linear mixed effect models were computed for each test. Few differences in performance were found on tests of EF and WM between PHIV and PHEU youth as they aged, though PHEU youth showed significantly better PS as they aged than PHIV youth. Future research is needed to understand these vulnerable youth's neurocognitive trajectories as a function of HIV infection and -exposure, biological functions and psychosocial stressors. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|