Histological and Transmission Electron Microscopy Results after Embolization with HydroSoft/HydroFrame Coils in Experimental Swine Aneurysm.
Coiling and clipping are standard treatment strategies for cerebral aneurysms. Regardless of the strategy used, recanalization may affect the patient's prognosis. The aim of this study was to histologically and morphologically compare the tissue proliferation after coil embolization using bare plati...
| Published in: | BioMed Research International pp. 1 - 10 |
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| Main Authors: | , , , , , , , , , , |
| Format: | diagnostic images pictorial research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
12/5/2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=140102705&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 140102705 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 12/5/2019 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 140102705 140102705 140102705 10.1155/2019/4834535 140102705 ppf: 1 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Histological and Transmission Electron Microscopy Results after Embolization with HydroSoft/HydroFrame Coils in Experimental Swine Aneurysm. aug: au: Iseki, Seisuke Mitome-Mishima, Yumiko Ogino, Ikuko Suga, Yasuo Yatomi, Kenji Nonaka, Senshu Miyamoto, Nobukazu Kondo, Akihide Yamamoto, Munetaka Arai, Hajime Oishi, Hidenori affil: Department of Neurosurgery, Ota General Hospital, Kawasaki, Kanagawa 210-0024, Japan sug: subj: Histological Techniques Methods Microscopy, Electron Gels Platinum Compounds Embolization, Therapeutic Methods Cerebral Aneurysm Surgery Postoperative Period Epithelial Cells Analysis Cell Proliferation Evaluation Animal Studies Swine Immunohistochemistry Recurrence Treatment Outcomes ab: Coiling and clipping are standard treatment strategies for cerebral aneurysms. Regardless of the strategy used, recanalization may affect the patient's prognosis. The aim of this study was to histologically and morphologically compare the tissue proliferation after coil embolization using bare platinum coils versus second-generation hydrogel coils (HydroSoft/HydroFrame; MicroVention, Inc., Aliso Viejo, CA, USA). Endothelial-like cell proliferation was seen in both groups at 2 weeks after surgery. Macroscopic findings showed a tighter layer at 4 weeks in the hydrogel coil group, and histological and immunohistochemical findings revealed endothelial cell proliferation. This layer became much thicker and tighter at 4 weeks after surgery. Aneurysms treated with second-generation hydrogel coils may be more stable and have a lower incidence of recanalization than those treated with bare platinum coils because of the tight endothelial layer proliferation. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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