A behavioral economic analysis of the effects of rimcazole on reinforcing effects of cocaine injection and food presentation in rats.

Rationale and objectives: Rimcazole, a σ-receptor antagonist with affinity for the dopamine transporter (DAT), decreases rates of cocaine self-administration at doses lower than those that affect food-reinforced responding. As response rates are multiply determined, behavioral-economic analyses were...

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Bibliographic Details
Published in:Psychopharmacology Vol. 236; no. 12; pp. 3601 - 3613
Main Authors: Job, Martin O., Katz, Jonathan L.
Format: Journal Article
Published: Springer Nature Dec2019
Online Access:View this record in EBSCOhost