Automatic Annotation of Retinal Layers in Optical Coherence Tomography Images.

Early diagnosis of retinal OCT images has been shown to curtail blindness and visual impairments. However, the advancement of ophthalmic imaging technologies produces an ever-growing scale of retina images, both in volume and variety, which overwhelms the ophthalmologist ability to segment these ima...

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Publicado en:Journal of Medical Systems Vol. 43; no. 12; pp. 1 - 11
Autores principales: Dodo, Bashir Isa, Li, Yongmin, Eltayef, Khalid, Liu, Xiaohui
Formato: diagnostic images equations & formulas research Journal Article
Publicado: Springer Nature Dec2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2019
      vid: 43
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-019-1452-9
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        atl: Automatic Annotation of Retinal Layers in Optical Coherence Tomography Images.
      aug:
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          Dodo, Bashir Isa
          Li, Yongmin
          Eltayef, Khalid
          Liu, Xiaohui
        affil: Department of Computer Science, Brunel University London, Kingston Lane, UB83PH, Uxbridge, UK
      sug:
        subj:
          Image Processing, Computer Assisted
          Image Enhancement
          Tomography, Optical Coherence
          Retinal Diseases Diagnosis
          Human
          Nerve Fibers Pathology
      ab: Early diagnosis of retinal OCT images has been shown to curtail blindness and visual impairments. However, the advancement of ophthalmic imaging technologies produces an ever-growing scale of retina images, both in volume and variety, which overwhelms the ophthalmologist ability to segment these images. While many automated methods exist, speckle noise and intensity inhomogeneity negatively impacts the performance of these methods. We present a comprehensive and fully automatic method for annotation of retinal layers in OCT images comprising of fuzzy histogram hyperbolisation (FHH) and graph cut methods to segment 7 retinal layers across 8 boundaries. The FHH handles speckle noise and inhomogeneity in the preprocessing step. Then the normalised vertical image gradient, and it's inverse to represent image intensity in calculating two adjacency matrices and then the FHH reassigns the edge-weights to make edges along retinal boundaries have a low cost, and graph cut method identifies the shortest-paths (layer boundaries). The method is evaluated on 150 B-Scan images, 50 each from the temporal, foveal and nasal regions were used in our study. Promising experimental results have been achieved with high tolerance and adaptability to contour variance and pathological inconsistency of the retinal layers in all (temporal, foveal and nasal) regions. The method also achieves high accuracy, sensitivity, and Dice score of 0.98360, 0.9692 and 0.9712, respectively in segmenting the retinal nerve fibre layer. The annotation can facilitate eye examination by providing accurate results. The integration of the vertical gradients into the graph cut framework, which captures the unique characteristics of retinal structures, is particularly useful in finding the actual minimum paths across multiple retinal layer boundaries. Prior knowledge plays an integral role in image segmentation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        Journal Article
      ougenre: Article
    language: English
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