A Framework for Automatic Morphological Feature Extraction and Analysis of Abdominal Organs in MRI Volumes.

The accurate 3D reconstruction of organs from radiological scans is an essential tool in computer-aided diagnosis (CADx) and plays a critical role in clinical, biomedical and forensic science research. The structure and shape of the organ, combined with morphological measurements such as volume and...

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Published in:Journal of Medical Systems Vol. 43; no. 12; pp. 1 - 11
Main Authors: Asaturyan, Hykoush, Thomas, E. Louise, Bell, Jimmy D., Villarini, Barbara
Format: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Published: Springer Nature Dec2019
Online Access:View this record in EBSCOhost
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      dt: Dec2019
      vid: 43
      iid: 12
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-019-1474-3
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        atl: A Framework for Automatic Morphological Feature Extraction and Analysis of Abdominal Organs in MRI Volumes.
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        au:
          Asaturyan, Hykoush
          Thomas, E. Louise
          Bell, Jimmy D.
          Villarini, Barbara
        affil: School of Computer Science and Engineering, University of Westminster, London, UK
      sug:
        subj:
          Abdomen Anatomy and Histology
          Imaging, Three-Dimensional Methods
          Magnetic Resonance Imaging
          Human
          Adult
          Conceptual Framework
          Pancreas
          Liver
          Descriptive Statistics
          Computing Methodologies
          Abdominal Fat
          Nonalcoholic Fatty Liver Disease
          Adult: 19-44 years
      ab: The accurate 3D reconstruction of organs from radiological scans is an essential tool in computer-aided diagnosis (CADx) and plays a critical role in clinical, biomedical and forensic science research. The structure and shape of the organ, combined with morphological measurements such as volume and curvature, can provide significant guidance towards establishing progression or severity of a condition, and thus support improved diagnosis and therapy planning. Furthermore, the classification and stratification of organ abnormalities aim to explore and investigate organ deformations following injury, trauma and illness. This paper presents a framework for automatic morphological feature extraction in computer-aided 3D organ reconstructions following organ segmentation in 3D radiological scans. Two different magnetic resonance imaging (MRI) datasets are evaluated. Using the MRI scans of 85 adult volunteers, the overall mean volume for the pancreas organ is 69.30 ± 32.50cm3, and the 3D global curvature is (35.23 ± 6.83) × 10−3. Another experiment evaluates the MRI scans of 30 volunteers, and achieves mean liver volume of 1547.48 ± 204.19cm3 and 3D global curvature (19.87 ± 3.62) × 10− 3. Both experiments highlight a negative correlation between 3D curvature and volume with a statistical difference (p < 0.0001). Such a tool can support the investigation into organ related conditions such as obesity, type 2 diabetes mellitus and liver disease.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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