Cerebrovascular events in hemodialysis patients; a retrospective observational study.
Background: This study reports findings in subjects who underwent brain imaging for any reason, and examined factors influencing cerebrovascular events (CVEs) in hemodialysis (HD) patients.Methods: We reviewed the files of patients on HD between January 2015 and January 2018. A total of 432 patients...
| Publicado en: | BMC Nephrology Vol. 20; no. 1; pp. 1 - 8 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
BioMed Central
12/12/2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=140312618&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 140312618 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14712369 1CI6 jtl: BMC Nephrology issn: 14712369 maglogo: N pubinfo: dt: 12/12/2019 vid: 20 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 140312618 140312618 NLM31830923 140312618 10.1186/s12882-019-1629-y NLM31830923 140312618 ppf: 1 ppct: 7 formats: tig: atl: Cerebrovascular events in hemodialysis patients; a retrospective observational study. aug: au: Ozelsancak, Ruya Micozkadioglu, Hasan Torun, Dilek Tekkarismaz, Nihan affil: Department of Nephrology, Adana Turgut Noyan Teaching and Research Center, Baskent University School of Medicine, Dadaloglu Mah, 39/6, Yuregir, 01250, Adana, PK, Turkey sug: subj: Kidney Failure, Chronic Therapy Kidney Failure, Chronic Cerebrovascular Disorders Etiology Cerebrovascular Disorders Hemodialysis Adverse Effects Kidney Failure, Chronic Blood Hemodialysis Trends Male Cerebrovascular Disorders Blood Adult Female Middle Age Aged Retrospective Design Human Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: This study reports findings in subjects who underwent brain imaging for any reason, and examined factors influencing cerebrovascular events (CVEs) in hemodialysis (HD) patients.Methods: We reviewed the files of patients on HD between January 2015 and January 2018. A total of 432 patients who underwent HD for at least 5 months by the January 2015 and who were older than 18 years were included in the study; 264 had been examined by cerebral computed tomography or magnetic resonance imaging examination within the 3 years. Cerebrovascular pathology was detected in 139 of 264 patients.Results: Of the 139 patients, 65 (24.62%) had ischemic lesions, 25 (9.47%) had hemorrhagic lesions, and 49 (18.56%) had cerebral small vessel disease (CSVD). We compared recorded data and later clinical findings between patients with and those without CVEs. The cause of end-stage renal disease was diabetes in 58.5% of patients with ischemic lesions, 52% in those with hemorrhagic lesions, and 55% in those with CSVD (P < 0.05). Patients with cerebrovascular ischemia were older (P = 0.0001) and had lower serum creatinine (sCr) (P = 0.0001) and higher serum C-reactive protein (CRP) (P = 0.002) levels than normal subjects. Hemorrhagic patients were older (P = 0.003) and had lower sCr (P = 0.003) and serum predialysis potassium (P = 0.003) and parathyroid hormone (PTH) (P = 0.004) levels than normal subjects. Patients with CSVD were older (P < 0.0001) and had lower sCr (P < 0.0001), phosphorus (P < 0.007), and PTH (P < 0.013) and higher CRP (P < 0.002) levels than normal subjects.Conclusions: HD patients with CVEs are older and typically have diabetes mellitus and lower sCr levels. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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