Symptom Clusters in Breast Cancer Survivors: A Latent Class Profile Analysis.

OBJECTIVES: To identify symptom clusters in breast cancer survivors and to determine sociodemographic and clinical characteristics influencing symptom cluster membership. SAMPLE & SETTING: The authors performed a crosssectional secondary analysis of data obtained from a community-based cancer regist...

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Publicado en:Oncology Nursing Forum Vol. 47; no. 1; pp. 89 - 101
Autores principales: Lee, Lena J., Ross, Alyson, Griffith, Kathleen, Jensen, Roxanne E., Wallen, Gwenyth R.
Formato: research tables/charts Journal Article
Publicado: Oncology Nursing Society Jan2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2020
      vid: 47
      iid: 1
      pid: 12496
      pub: Oncology Nursing Society
      place: Pittsburgh, Pennsylvania
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        140438863
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        10.1188/20.ONF.89-100
        140438863
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        atl: Symptom Clusters in Breast Cancer Survivors: A Latent Class Profile Analysis.
      aug:
        au:
          Lee, Lena J.
          Ross, Alyson
          Griffith, Kathleen
          Jensen, Roxanne E.
          Wallen, Gwenyth R.
        affil: Nurse scientists, National Institutes of Health Clinical Center in Bethesda, MD
      sug:
        subj:
          Breast Neoplasms Symptoms
          Cancer Survivors Psychosocial Factors
          Socioeconomic Factors
          Quality of Life
          Human
          Secondary Analysis
          Cross Sectional Studies
          Pain
          Fatigue
          Sleep Disorders
          Depression
          Cluster Analysis
          Structural Equation Modeling
          Coefficient alpha
          Descriptive Statistics
          Data Analysis Software
          Severity of Illness
          Comorbidity
          Confidence Intervals
          Odds Ratio
          Comparative Studies
          Factor Analysis
          Regression
          Patient-Reported Outcomes
          Clinical Assessment Tools
      ab: OBJECTIVES: To identify symptom clusters in breast cancer survivors and to determine sociodemographic and clinical characteristics influencing symptom cluster membership. SAMPLE & SETTING: The authors performed a crosssectional secondary analysis of data obtained from a community-based cancer registry-linked survey with 1,500 breast cancer survivors 6-13 months following a breast cancer diagnosis. METHODS & VARIABLES: Symptom clusters were identified using latent class profile analysis of four patient-reported symptoms (pain, fatigue, sleep disturbance, and depression) with custom PROMIS® short forms. RESULTS: Four distinct classes were identified: symptoms within normal limits (class 1), pain with fatigue and sleep disturbance (class 2), depression with fatigue and sleep disturbance (class 3), and all high symptom burden (class 4). The authors identified four clinically relevant and actionable symptom clusters in early-stage breast cancer survivorship. Certain sociodemographic and clinical characteristics place patients at risk for physical late effects and mental health issues. IMPLICATIONS FOR NURSING: Common symptom clusters may lead to better prevention and treatment strategies that target a group of symptoms. Results also suggest that certain factors place patients at high risk for symptom burden, which can guide tailored interventions.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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