How Should We Define Clinically Significant Improvement on Patient-Reported Outcomes Measurement Information System Test for Patients Undergoing Knee Meniscal Surgery?

Purpose: The purpose of the study was to define the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptomatic state (PASS) thresholds for the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) computer...

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Publicado en:Arthroscopy: The Journal of Arthroscopy & Related Surgery Vol. 36; no. 1; pp. 241 - 251
Autores principales: Okoroha, Kelechi R, Lu, Yining, Nwachukwu, Benedict U, Beletsky, Alexander, Patel, Bhavik H, Verma, Nikhil N, Cole, Brian, Forsythe, Brian
Formato: research Journal Article
Publicado: Wiley-Blackwell Jan2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1016/j.arthro.2019.07.036
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        atl: How Should We Define Clinically Significant Improvement on Patient-Reported Outcomes Measurement Information System Test for Patients Undergoing Knee Meniscal Surgery?
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        au:
          Okoroha, Kelechi R
          Lu, Yining
          Nwachukwu, Benedict U
          Beletsky, Alexander
          Patel, Bhavik H
          Verma, Nikhil N
          Cole, Brian
          Forsythe, Brian
        affil: Division of Sports Medicine, Midwest Orthopaedics at Rush, Rush University Medical Center, Chicago, Illinois, U.S.A
      sug:
        subj:
          Knee Injuries Surgery
          Arthroscopy Methods
          Knee Joint Surgery
          ROC Curve
          Male
          Retrospective Design
          Adult
          Female
          Middle Age
          Postoperative Period
          Treatment Outcomes
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: The purpose of the study was to define the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptomatic state (PASS) thresholds for the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) computerized adaptive test (CAT) instrument in patients undergoing arthroscopic meniscal surgery.Methods: The PROMIS PF CAT was administered preoperatively and postoperatively to patients undergoing arthroscopic meniscal surgery. At 6 months postoperatively, patients graded their knee function based on a domain-specific anchor question. A satisfaction anchor question was used to indicate achievement of the PASS. Receiver operating characteristic analysis determined the relevant psychometric values. Cutoff analysis was performed to find preoperative patient-reported outcome scores predicting achievement of clinically significant outcomes (CSOs).Results: A total of 73 patients (41.1% female patients) were included, with a mean age of 44.9 ± 12.8.0 years and average follow-up period of 24.0 ± 1.2 weeks. The MCID on the PROMIS PF CAT was calculated to be 2.09 (area under the curve [AUC], 0.75; 95% CI, 0.57-0.94). Net score improvement equivalent to achievement of SCB was found to be 6.50 (AUC, 0.77; 95% CI, 0.55-0.99). The PASS was found to be 46.1 (AUC, 0.86; 95% CI, 0.76-0.96). A preoperative score below 37.6 on the PROMIS PF CAT predicted achievement of the MCID (AUC, 0.76; 95% CI, 0.62-0.87), whereas scores above 41.9 predicted achievement of the PASS (AUC, 0.77; 95% CI, 0.65-0.90). Higher baseline functional status and the absence of pre-existing arthritis were also found to be statistically significant predictors of achieving CSOs.Conclusions: Our study defined the MCID, SCB, and PASS for the PROMIS PF CAT. We found that a preoperative score below 37.6 was predictive of achieving a meaningful clinical change with surgery whereas a preoperative score above 41.9 was predictive of patients who would attain an acceptable postoperative health state. In addition, exercising more days per week and the absence of arthritis increased the likelihood of achieving postoperative CSOs.Level Of Evidence: Level III, retrospective cohort.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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