Myocardial deformation and acute cellular rejection after heart transplantation: Impact of inter‐vendor variability in diagnostic effectiveness.
Purpose: Our objective was to investigate the impact of inter‐vendor variability in the ability of myocardial strain analysis to detect acute cellular rejection (ACR) in heart transplant recipients. Methods: We performed serial echocardiographic examinations in 18 consecutive adult heart transplante...
| Publicado en: | Echocardiography Vol. 36; no. 12; pp. 2185 - 2195 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Dec2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=140853483&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 140853483 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Dec2019 vid: 36 iid: 12 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 140853483 140853483 140853483 10.1111/echo.14544 140853483 ppf: 2185 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Myocardial deformation and acute cellular rejection after heart transplantation: Impact of inter‐vendor variability in diagnostic effectiveness. aug: au: Ruiz‐Ortiz, Martín Rodriguez‐Diego, Sara Delgado, Mónica Kim, Jiwon Weinsaft, Jonathan W. Ortega, Rosa Carnero, Lucía Sánchez, José J. Carrasco, Francisco López‐Aguilera, José López‐Granados, Amador Arizón, José M. Paredes, Nick Oneto‐Fernandez, Jesús Pan, Manuel Mesa, Dolores affil: Cardiology Department, Reina Sofia University Hospital, Cordoba Spain sug: subj: Transplant Recipients Heart Transplantation Postoperative Complications Myocardium Physiopathology Graft Rejection Outcomes (Health Care) Human Echocardiography Methods Quantitative Studies Descriptive Statistics T-Tests Analysis of Variance Data Analysis Software ab: Purpose: Our objective was to investigate the impact of inter‐vendor variability in the ability of myocardial strain analysis to detect acute cellular rejection (ACR) in heart transplant recipients. Methods: We performed serial echocardiographic examinations in 18 consecutive adult heart transplanted patients, in their first year post‐transplantation, within 3 hours of the routine surveillance endomyocardial biopsies (EMB) in a single center. Myocardial strain was analyzed using two software in two different institutions, and inter‐vendor variability of strain values and its association with ACR (any grade or grade ≥2R) was investigated. The parameter of comparison was the peak value of the average curve of strain during the entire cardiac cycle. Results: A total of 147 pairs of EMB‐echocardiogram were performed, 65 with no ACR, 63 with ACR grade 1R, and 19 with ACR grade ≥2R. Intra‐class correlation coefficients for left ventricle longitudinal, radial, and circumferential strain were 0.38, 0.39, and 0.77, respectively, and 0.32 for right ventricular longitudinal strain. Neither software found significant association of left ventricular longitudinal strain with rejection. Grade ≥2R ACR was associated with left ventricular circumferential strain measured with the first software and with left ventricular radial strain with the other; and ACR of any grade was only significantly associated with right ventricle longitudinal strain measured with the first software. Conclusions: Inter‐vendor reproducibility of strain values was low in this study. Some strain parameters were associated to ACR, although these results were inconsistent between two commercially available software. Specific validation of each software is warranted for this clinical indication. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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