The effect of propofol on frontal QRS‐T angle in patients undergoing elective colonoscopy procedure.
What is known and objective: Propofol is a most commonly used anaesthetic drug for conscious sedation in outpatient procedures. Previous studies have shown that propofol may affect ventricular repolarization based on QT and Tp‐e intervals. Frontal QRS‐T angle is a marker of ventricular depolarizatio...
| Publicado en: | Journal of Clinical Pharmacy & Therapeutics Vol. 45; no. 1; pp. 185 - 191 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Feb2020
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141002026&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141002026 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02694727 EV4 jtl: Journal of Clinical Pharmacy & Therapeutics issn: 02694727 maglogo: Y pubinfo: dt: Feb2020 vid: 45 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 141002026 141002026 141002026 10.1111/jcpt.13055 141002026 ppf: 185 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: The effect of propofol on frontal QRS‐T angle in patients undergoing elective colonoscopy procedure. aug: au: Tascanov, Mustafa Begenc Tanriverdi, Zulkif Gungoren, Fatih Besli, Feyzullah Bicer Yesilay, Asuman Altiparmak, Halil Ibrahim Bayram, Gursel Demir, Kadir affil: Department of Cardiology, Faculty of Medicine, Harran University, Sanliurfa Turkey sug: subj: Surgery, Elective Colposcopy Propofol Pharmacodynamics QRS Complex Human Female Male Surgical Patients Pre-Excitation Syndromes Heart Ventricle Drug Effects Female Male ab: What is known and objective: Propofol is a most commonly used anaesthetic drug for conscious sedation in outpatient procedures. Previous studies have shown that propofol may affect ventricular repolarization based on QT and Tp‐e intervals. Frontal QRS‐T angle is a marker of ventricular depolarization and repolarization difference. However, there is no study investigating the effect of propofol on frontal QRS‐T angle. In this study, we aimed to investigate the effect of propofol on frontal QRS‐T angle in patients undergoing colonoscopy procedure. Method: A total of 56 patients (53.5% females) who underwent colonoscopy procedure were included in this study. All patients underwent 12‐lead surface electrocardiograms (ECGs) just before colonoscopy and 15 minutes after colonoscopy. QT interval, QTc interval, Tp‐e interval, Tp‐e/QT, Tp‐e/QTc and frontal QRS‐T angle were calculated from 12‐lead ECGs. Results and discussion: The frontal QRS‐T angle was significantly increased 15 minutes after colonoscopy compared to basal value (36.2 ± 24.3 vs. 29.5 ± 23.6, P =.003). In addition, repolarization parameters including QT, QTc and Tp‐e intervals were significantly prolonged at 15 minutes after colonoscopy compared to basal value, except Tp‐e/QT and Tp‐e/QTc. Significant ventricular or supraventricular arrhythmias were not observed in any patient during the procedure. What is new and conclusion: In this study, we found that propofol administration increased the frontal QRS‐T angle in patients undergoing colonoscopy procedure. Given that a prolonged frontal QRS‐T angle is associated with ventricular arrhythmias, it may be safer to monitor those patients receiving propofol during colonoscopy procedures. pubtype: Academic Journal doctype: research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|