α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.

Parkinson's disease is one of the most common movement disorders and is characterized by dopaminergic cell loss and the accumulation of pathological α-synuclein, but its precise pathogenetic mechanisms remain elusive. To develop disease-modifying therapies for Parkinson's disease, an animal model th...

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Bibliographic Details

Published in:	Brain: A Journal of Neurology Vol. 142; no. 1; pp. 249 - 266
Main Authors:	Taguchi, Tomoyuki, Ikuno, Masashi, Hondo, Mari, Parajuli, Laxmi Kumar, Taguchi, Katsutoshi, Ueda, Jun, Sawamura, Masanori, Okuda, Shinya, Nakanishi, Etsuro, Hara, Junko, Uemura, Norihito, Hatanaka, Yusuke, Ayaki, Takashi, Matsuzawa, Shuichi, Tanaka, Masaki, El-Agnaf, Omar M A, Koike, Masato, Yanagisawa, Masashi, Uemura, Maiko T, Yamakado, Hodaka
Format:	research Journal Article
Published:	Oxford University Press / USA Jan2019
Online Access:	View this record in EBSCOhost