Infantile hepatic hemangioma: current state of the art, controversies, and perspectives.

Infantile hepatic hemangioma (IHH) is a common vascular tumor, distinctive for its perinatal presentation, rapid growth during the first year of life, and subsequent involution. Although they generally follow a benign course, some tumors have been reported to undergo malignant transformation. The di...

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Publicado en:European Journal of Pediatrics Vol. 179; no. 1; pp. 1 - 9
Autores principales: Zavras, Nikolaos, Dimopoulou, Anastasia, Machairas, Nikolaos, Paspala, Anna, Vaos, George
Formato: review tables/charts Journal Article
Publicado: Springer Nature Jan2020
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Infantile hepatic hemangioma: current state of the art, controversies, and perspectives.
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          Zavras, Nikolaos
          Dimopoulou, Anastasia
          Machairas, Nikolaos
          Paspala, Anna
          Vaos, George
        affil: Department of Paediatric Surgery, "ATTIKON" General University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
      sug:
        subj:
          Liver Neoplasms Etiology
          Liver Neoplasms Epidemiology
          Liver Neoplasms Diagnosis
          Hemangioma Epidemiology
          Liver Neoplasms Therapy
          Hemangioma Therapy
          Hemangioma Etiology
          Hemangioma Diagnosis
          Prognosis
          Child, Preschool
          Diagnosis, Differential
          Infant
          Child
          Infant, Newborn
          Combined Modality Therapy
          World Health
          Child, Preschool: 2-5 years
          Infant: 1-23 months
          Child: 6-12 years
          Infant, Newborn: birth-1 month
      ab: Infantile hepatic hemangioma (IHH) is a common vascular tumor, distinctive for its perinatal presentation, rapid growth during the first year of life, and subsequent involution. Although they generally follow a benign course, some tumors have been reported to undergo malignant transformation. The diagnosis of IHH is based on patient's medical history, physical examination, and imaging. Moreover, the management of this vascular tumor is based on clinical presentation and includes observational, medical, surgical, and radiological interventional treatment options. The present review presents the currently available data in the literature on the diverse aspects of the terminology, epidemiology, clinical presentation, pathogenesis, diagnosis, indications for surgery, malignant potential, and long-term outcomes of these tumors.Conclusion: No formal guidelines have yet been established for the treatment of these hepatic lesions, and the therapeutic strategies implemented vary widely from simple observation to medical, radiological, and surgical interventions in the prism of multidisciplinary teams.What is Known:• Infantile hepatic hemangioma is the most common benign tumor of the liver in infancy, but despite its benign nature, it can present with life-threatening complications.• The treatment strategies range from simple observation to a series of medical, surgical, and radiological interventions.What is New:• This review gives an overview of the developments and current status about the management of IHH.• The aim of this study is to clear up the confusion and controversy that exists about terminology, diagnosis, and treatment of IHH.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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