Imaging mimics of chronic recurrent multifocal osteomyelitis: avoiding pitfalls in a diagnosis of exclusion.

Chronic recurrent multifocal osteomyelitis (CRMO) is a pediatric autoinflammatory disorder that is characterized by multiple sterile inflammatory bone lesions with a relapsing and remitting course. CRMO belongs to the autoinflammatory family of rheumatologic disorders based on absence of significant...

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Publicado en:Pediatric Radiology Vol. 50; no. 1; pp. 124 - 137
Autores principales: Sato, Takashi Shawn, Watal, Pankaj, Ferguson, Polly J.
Formato: review Journal Article
Publicado: Springer Nature Jan2020
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Imaging mimics of chronic recurrent multifocal osteomyelitis: avoiding pitfalls in a diagnosis of exclusion.
      aug:
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          Sato, Takashi Shawn
          Watal, Pankaj
          Ferguson, Polly J.
        affil: Division of Pediatric Radiology, Department of Radiology, Stead Family Children's Hospital, University of Iowa, 200 Hawkins Drive, 3889 JPP, 52242, Iowa City, IA, USA
      sug:
        subj:
          Radiography Methods
          Osteomyelitis
          Magnetic Resonance Imaging Methods
          Diagnosis, Differential
          Male
          Child
          Female
          Clinical Assessment Tools
          Scales
          Child: 6-12 years
          Male
          Female
      ab: Chronic recurrent multifocal osteomyelitis (CRMO) is a pediatric autoinflammatory disorder that is characterized by multiple sterile inflammatory bone lesions with a relapsing and remitting course. CRMO belongs to the autoinflammatory family of rheumatologic disorders based on absence of significant titers of autoantibodies and autoreactive T-lymphocytes. In absence of pathognomonic clinical, radiographic or pathological features, diagnosis can be challenging. CRMO shares imaging features with other diseases. It is important for radiologists to be able to differentiate other diseases from CRMO because prognosis varies from completely benign to frankly malignant. In this article we first present the clinical and imaging features of CRMO to help readers gain an understanding of the disease process, then discuss our imaging approach to CRMO and review other disease processes that sometimes share similar imaging findings to CRMO and review differentiating features to help avoid misdiagnoses.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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