Validation of a Proposed Algorithm for Assistance Titration During Proportional Assist Ventilation With Load-Adjustable Gain Factors.
BACKGROUND: The present study aimed to validate a recently proposed algorithm for assistance titration during proportional assist ventilation with load-adjustable gain factors, based on a noninvasive estimation of maximum inspiratory pressure (peak Pmus) and inspiratory effort (pressure-time product...
| Publicado en: | Respiratory Care Vol. 65; no. 1; pp. 36 - 45 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | CEU equations & formulas research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Jan2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141064440&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141064440 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jan2020 vid: 65 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 141064440 141064440 141064440 10.4187/respcare.06988 141064440 ppf: 36 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Validation of a Proposed Algorithm for Assistance Titration During Proportional Assist Ventilation With Load-Adjustable Gain Factors. aug: au: Amargiannitakis, Vasilios Gialamas, Ioannis Pediaditis, Emmanouil Soundoulounaki, Stella Prinianakis, Georgios Vaporidi, Katerina Akoumianaki, Evangelia Proklou, Athanasia Alexopoulou, Christina Georgopoulos, Dimitrios Kondili, Eumorfia affil: Department of Intensive Care Medicine, University Hospital of Heraklion and School of Medicine, University of Crete, Heraklion, Crete, Greece sug: subj: Algorithms Evaluation Respiration, Artificial Methods Human Academic Medical Centers Greece Retrospective Design Sensitivity and Specificity Airway Pressure Respiratory Muscles Physiology Pressure Support Ventilation Ventilator Weaning Inspiration, Respiratory Descriptive Statistics Linear Regression Data Analysis Software ROC Curve Spearman's Rank Correlation Coefficient Education, Continuing (Credit) ab: BACKGROUND: The present study aimed to validate a recently proposed algorithm for assistance titration during proportional assist ventilation with load-adjustable gain factors, based on a noninvasive estimation of maximum inspiratory pressure (peak Pmus) and inspiratory effort (pressure-time product [PTP] peak Pmus). METHODS: Retrospective analysis of the recordings obtained from 26 subjects ventilated on proportional assist ventilation with load-adjustable gain factors under different conditions, each considered as an experimental case. The estimated inspiratory output (peak Pmus) and effort (PTP-peak Pmus) were compared with the actual-determined by the measurement of transdiaphragmatic pressure- and the derived PTP. Validation of the algorithm was performed by assessing the accuracy of peak Pmus in predicting the actual inspiratory muscle effort and indicating the appropriate level of assist. RESULTS: In the 63 experimental cases analyzed, a limited agreement was observed between the estimated and the actual inspiratory muscle pressure (-11 to 10 cm H2O) and effort (-82 to 125 cm H2O x s/min). The sensitivity and specificity of peak Pmus to predict the range of the actual inspiratory effort was 81.2% and 58.1%, respectively. In 49% of experimental cases, the level of assist indicated by the algorithm differed from that indicated by the transdiaphragmatic pressure and PTP. CONCLUSIONS: The proposed algorithm had limited accuracy in estimating inspiratory muscle effort and with indicating the appropriate level of assist. pubtype: Academic Journal doctype: CEU equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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