Potential of machine learning methods to identify patients with nonvalvular atrial fibrillation.

Aim: Nonvalvular atrial fibrillation (NVAF) is associated with an increased risk of stroke however many patients are diagnosed after onset. This study assessed the potential of machine-learning algorithms to detect NVAF. Materials & methods: A retrospective database study using a Japanese claims dat...

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Publicado en:Future Cardiology Vol. 16; no. 1; pp. 43 - 52
Autores principales: Suzuki, Ryoko, Katada, Jun, Ramagopalan, Sreeram, McDonald, Laura
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jan2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2020
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      pub: Taylor & Francis Ltd
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        10.2217/fca-2019-0056
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        atl: Potential of machine learning methods to identify patients with nonvalvular atrial fibrillation.
      aug:
        au:
          Suzuki, Ryoko
          Katada, Jun
          Ramagopalan, Sreeram
          McDonald, Laura
        affil: Cardiovascular Medical, Bristol-Myers Squibb K.K., Tokyo, Japan
      sug:
        subj:
          Stroke Prevention and Control
          Atrial Fibrillation Diagnosis
          Algorithms
          Male
          Prospective Studies
          Retrospective Design
          Risk Factors
          Stroke Etiology
          Atrial Fibrillation Complications
          Aged
          Female
          Human
          Aged: 65+ years
          Male
          Female
      ab: Aim: Nonvalvular atrial fibrillation (NVAF) is associated with an increased risk of stroke however many patients are diagnosed after onset. This study assessed the potential of machine-learning algorithms to detect NVAF. Materials & methods: A retrospective database study using a Japanese claims database. Patients with and without NVAF were selected. 41 variables were included in different classification algorithms. Results: Machine learning algorithms identified NVAF with an area under the curve of >0.86; corresponding sensitivity/specificity was also high. The stacking model which combined multiple algorithms outperformed single-model approaches (area under the curve ≥0.90, sensitivity/specificity ≥0.80/0.82), although differences were small. Conclusion: Machine-learning based algorithms can detect atrial fibrillation with accuracy. Although additional validation is needed, this methodology could encourage a new approach to detect NVAF.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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