Evidence for positive allosteric modulation of cognitive-enhancing effects of nicotine in healthy human subjects.

Rationale: Cognitive benefits of nicotinic acetylcholine receptor (nAChR) agonists are well established but have generally been of small magnitude and uncertain clinical significance. A way of raising the effect size may be to facilitate agonist-induced responses by co-administering a nAChR positive...

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Publicado en:Psychopharmacology Vol. 237; no. 1; pp. 219 - 231
Autores principales: Hahn, Britta, Shrieves, Megan E., Olmstead, Cory K., Yuille, Marie B., Chiappelli, Joshua J., Pereira, Edna F. R., Albuquerque, Edson X., Fawcett, William P.
Formato: Journal Article
Publicado: Springer Nature Jan2020
Acceso en línea:Ver este registro en EBSCOhost