Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018.

Prevention of HIV outbreaks among people who inject drugs remains a challenge to ending the HIV epidemic in the United States. The first legal syringe services program (SSP) in Florida implemented routine screening in 2018 leading to the identification of ten anonymous HIV seroconversions. The SSP c...

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Publicado en:AIDS & Behavior Vol. 24; no. 1; pp. 246 - 257
Autores principales: Tookes, Hansel, Bartholomew, Tyler S., Geary, Shana, Matthias, James, Poschman, Karalee, Blackmore, Carina, Philip, Celeste, Suarez, Edward, Forrest, David W., Rodriguez, Allan E., Kolber, Michael A., Knaul, Felicia, Colucci, Leah, Spencer, Emma
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jan2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10461-019-02680-9
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        atl: Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018.
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          Tookes, Hansel
          Bartholomew, Tyler S.
          Geary, Shana
          Matthias, James
          Poschman, Karalee
          Blackmore, Carina
          Philip, Celeste
          Suarez, Edward
          Forrest, David W.
          Rodriguez, Allan E.
          Kolber, Michael A.
          Knaul, Felicia
          Colucci, Leah
          Spencer, Emma
        affil: University of Miami, 1120 NW 14th St #860, 33136, Miami, FL, USA
      sug:
        subj:
          HIV Infections Risk Factors
          HIV Infections Transmission
          HIV Infections Prevention and Control
          Seroconversion
          Substance Abuse Prevention and Control
          Viral Load
          Early Diagnosis
          Needle Exchange Programs
          Harm Reduction
          Human
          Florida
          Genotype
          HIV Infections Familial and Genetic
          Patient Navigation
          Contact Tracing
          Disease Outbreaks
          HIV Infections Diagnosis
          Collaboration
          HIV Infections Epidemiology
          Program Implementation
      ab:
        Prevention of HIV outbreaks among people who inject drugs remains a challenge to ending the HIV epidemic in the United States. The first legal syringe services program (SSP) in Florida implemented routine screening in 2018 leading to the identification of ten anonymous HIV seroconversions. The SSP collaborated with the Department of Health to conduct an epidemiologic investigation. All seven acute HIV seroconversions were linked to care (86% within 30 days) and achieved viral suppression (mean 70 days). Six of the seven individuals are epidemiologically and/or socially linked to at least two other seroconversions. Analysis of the HIV genotypes revealed that two individuals are connected molecularly at 0.5% genetic distance. We identified a risk network with complex transmission dynamics that could not be explained by epidemiological methods or molecular analyses alone. Providing wrap-around services through the SSP, including routine screening, intensive linkage and patient navigation, could be an effective model for achieving viral suppression for people who inject drugs.
        Resumen: La prevención de brotes de VIH entre las personas que se inyectan drogas sigue siendo un desafío para poner fin a la epidemia de VIH en los Estados Unidos. El primer programa legal de servicios de intercambio de jeringas (SSP como se conoce con sus siglas en inglés) en Florida, implementó pruebas rutinarias en 2018 que condujo a la identificación de diez seroconversiones anónimas de VIH. El SSP colaboró ​​con el Departamento de Salud para realizar una investigación epidemiológica. Siete seroconversiones agudas de VIH fueron identificadas y se vincularon a la atención médica (86% en 30 días) y lograron la supresión viral (media 70 días). Seis de los siete individuos están vinculados epidemiológicamente y/o socialmente con al menos otras dos seroconversiones. El análisis de los genotipos del VIH reveló que dos individuos están conectados molecularmente a una distancia genética de 0.5%. Identificamos una red de riesgo con una dinámica de transmisión compleja que no puede explicarse solamente con métodos epidemiológicos o análisis moleculares. Brindando servicios integrales a través del SSP, que incluyan pruebas de rutina, el enlace intensivo y la navegación del paciente, podría ser un modelo eficaz para lograr la supresión viral de las personas que se inyectan drogas.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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