Myocardial extracellular volume quantification in cardiac CT: comparison of the effects of two different iterative reconstruction algorithms with MRI as a reference standard.

Objectives: To compare the effects of hybrid iterative reconstruction (HIR) and model-based iterative reconstruction (MBIR) that incorporates a beam-hardening model for myocardial extracellular volume (ECV) quantification by cardiac CT using MRI as a reference standard.Methods: In this retrospective...

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Publicado en:European Radiology Vol. 30; no. 2; pp. 691 - 702
Autores principales: Emoto, Takafumi, Kidoh, Masafumi, Oda, Seitaro, Nakaura, Takeshi, Nagayama, Yasunori, Sasao, Akira, Funama, Yoshinori, Araki, Satoshi, Takashio, Seiji, Sakamoto, Kenji, Yamamoto, Eiichiro, Kaikita, Koichi, Tsujita, Kenichi, Yamashita, Yasuyuki
Formato: research Journal Article
Publicado: Springer Nature Feb2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2020
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-019-06418-y
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        atl: Myocardial extracellular volume quantification in cardiac CT: comparison of the effects of two different iterative reconstruction algorithms with MRI as a reference standard.
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          Emoto, Takafumi
          Kidoh, Masafumi
          Oda, Seitaro
          Nakaura, Takeshi
          Nagayama, Yasunori
          Sasao, Akira
          Funama, Yoshinori
          Araki, Satoshi
          Takashio, Seiji
          Sakamoto, Kenji
          Yamamoto, Eiichiro
          Kaikita, Koichi
          Tsujita, Kenichi
          Yamashita, Yasuyuki
        affil: Department of Central Radiology, Kumamoto University Hospital, 1-1-1 Honjyo, Chuo-ku, 860-8556, Kumamoto, Japan
      sug:
        subj:
          Algorithms
          Tomography, X-Ray Computed Methods
          Magnetic Resonance Imaging
          Heart Diseases
          Radiographic Image Interpretation, Computer-Assisted Methods
          Heart
          Myocardium Pathology
          Heart Diseases Pathology
          Retrospective Design
          Human
          Male
          Middle Age
          Body Weights and Measures
          Female
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Scales
          Middle Aged: 45-64 years
          Male
          Female
      ab: Objectives: To compare the effects of hybrid iterative reconstruction (HIR) and model-based iterative reconstruction (MBIR) that incorporates a beam-hardening model for myocardial extracellular volume (ECV) quantification by cardiac CT using MRI as a reference standard.Methods: In this retrospective study, a total of 34 patients were evaluated using cardiac CT and MRI. Paired CT image sets were created using HIR and MBIR with a beam-hardening model. We calculated mean absolute differences and correlations between the global mid-ventricular ECV derived from CT and MRI via Pearson correlation analysis. In addition, we performed qualitative analysis of image noise and beam-hardening artifacts on postcontrast images using a four-point scale: 1 = extensive, 2 = strong, 3 = mild, and 4 = minimal.Results: The mean absolute difference between the ECV derived from CT and MRI for MBIR was significantly smaller than that for HIR (MBIR 3.74 ± 3.59%; HIR 4.95 ± 3.48%, p = 0.034). MBIR improved the correlation between the ECV derived from CT and MRI when compared with HIR (MBIR, r = 0.60, p < 0.001; HIR, r = 0.47, p = 0.006). In qualitative analysis, MBIR significantly reduced image noise and beam-hardening artifacts when compared with HIR ([image noise, MBIR 3.4 ± 0.7; HIR 2.1 ± 0.8, p < 0.001], [beam-hardening artifacts, MBIR 3.8 ± 0.4; HIR 2.6 ± 1.0, p < 0.001]).Conclusions: MBIR with a beam-hardening model effectively reduced image noise and beam-hardening artifacts and improved myocardial ECV quantification when compared with HIR using MRI as a reference standard.Key Points: • MBIR with a beam-hardening model effectively reduced image noise and beam-hardening artifacts. • The mean absolute difference between the global mid-ventricular ECV derived from CT and MRI for MBIR was significantly smaller than that for conventional HIR. • MBIR provided more accurate myocardial CT number and improved ECV quantification when compared with HIR.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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