STEPS: an efficient prospective likelihood approach to genetic association analyses of secondary traits in extreme phenotype sequencing.

It has been well acknowledged that methods for secondary trait (ST) association analyses under a case-control design (ST$_{\text{CC}}$) should carefully consider the sampling process to avoid biased risk estimates. A similar situation also exists in the extreme phenotype sequencing (EPS) designs, wh...

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Detalles Bibliográficos
Publicado en:Biostatistics Vol. 21; no. 1; pp. 33 - 50
Autores principales: Bi, Wenjian, Li, Yun, Smeltzer, Matthew P, Gao, Guimin, Zhao, Shengli, Kang, Guolian
Formato: research Journal Article
Publicado: Oxford University Press / USA Jan2020
Acceso en línea:Ver este registro en EBSCOhost