Evaluating DREAMS HIV prevention interventions targeting adolescent girls and young women in high HIV prevalence districts in South Africa: protocol for a cross-sectional study.

Background: Young women in sub-Saharan Africa remain at the epicentre of the HIV epidemic, with surveillance data indicating persistent high levels of HIV incidence. In South Africa, adolescent girls and young women (AGYW) account for a quarter of all new HIV infections. Determined, Resilient, Empow...

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Published in:BMC Women's Health Vol. 20; no. 1; pp. 1 - 12
Main Authors: George, Gavin, Cawood, Cherie, Puren, Adrian, Khanyile, David, Gerritsen, Annette, Govender, Kaymarlin, Beckett, Sean, Glenshaw, Mary, Diallo, Karidia, Ayalew, Kassahun, Gibbs, Andrew, Reddy, Tarylee, Madurai, Lorna, Kufa-Chakezha, Tendesayi, Kharsany, Ayesha B. M.
Format: research Journal Article
Published: BioMed Central 1/16/2020
Online Access:View this record in EBSCOhost
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        atl: Evaluating DREAMS HIV prevention interventions targeting adolescent girls and young women in high HIV prevalence districts in South Africa: protocol for a cross-sectional study.
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          George, Gavin
          Cawood, Cherie
          Puren, Adrian
          Khanyile, David
          Gerritsen, Annette
          Govender, Kaymarlin
          Beckett, Sean
          Glenshaw, Mary
          Diallo, Karidia
          Ayalew, Kassahun
          Gibbs, Andrew
          Reddy, Tarylee
          Madurai, Lorna
          Kufa-Chakezha, Tendesayi
          Kharsany, Ayesha B. M.
        affil: Health Economics and HIV and AIDS Research Division (HEARD), 4th Floor, J Block, Westville Campus, University of KwaZulu-Natal, Durban, South Africa
      sug:
        subj:
          Preventive Health Care Methods
          HIV Infections Psychosocial Factors
          Preventive Health Care Administration
          Sexuality
          HIV Infections Epidemiology
          HIV Infections Prevention and Control
          Behavior
          South Africa
          Prevalence
          Prospective Studies
          Incidence
          Adolescence
          Cross Sectional Studies
          Human
          Young Adult
          Female
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Impact of Events Scale
          Adolescent: 13-18 years
          Female
      ab: Background: Young women in sub-Saharan Africa remain at the epicentre of the HIV epidemic, with surveillance data indicating persistent high levels of HIV incidence. In South Africa, adolescent girls and young women (AGYW) account for a quarter of all new HIV infections. Determined, Resilient, Empowered, AIDS-free, Mentored and Safe (DREAMS) is a strategy introduced by the United States President's Emergency Plan for AIDS Relief (PEPFAR) aimed at reducing HIV incidence among AGYW in 10 countries in sub-Saharan Africa by 25% in the programme's first year, and by 40% in the second year. This study will assess the change in HIV incidence and reduction in risk associated behaviours that can be attributed to the DREAMS initiative in South Africa, using a population-based cross-sectional survey.Methods: Data will be collected from a household-based representative sample of AGYW (between the ages 12-24 years) in four high prevalence districts (more than 10% of the population have HIV in these districts) in South Africa in which DREAMS has been implemented. A stratified cluster-based sampling approach will be used to select eligible participants for a cross-sectional survey with 18,500, to be conducted over 2017/2018. A questionnaire will be administered containing questions on sexual risk behaviour, selected academic and developmental milestones, prevalence of gender based violence, whilst examining exposure to DREAMS programmes. Biological samples, including two micro-containers of blood and self-collected vulvovaginal swab samples, are collected in each survey to test for HIV infection, HIV incidence, sexually transmitted infections (STIs) and pregnancy. This study will measure trends in population level HIV incidence using the Limiting antigen (LAg) Avidity Enzyme Immuno-Assay (EIA) and monitor changes in HIV incidence.Discussion: Ending the HIV/AIDS pandemic by 2030 requires the continual monitoring and evaluation of prevention programmes, with the aim of optimising efforts and ensuring the achievement of epidemic control. This study will determine the impact DREAMS interventions have had on HIV incidence among AGYW in a 'real world, non-trial setting'.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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