Measuring Similarity among Protein Sequences Using a New Descriptor.
+e comparison of protein sequences according to similarity is a fundamental aspect of today's biomedical research. With the developments of sequencing technologies, a large number of protein sequences increase exponentially in the public databases. Famous sequences' comparison methods are alignment...
| Publicado en: | BioMed Research International pp. 1 - 11 |
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| Autores principales: | , , |
| Formato: | equations & formulas review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
11/22/2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141408344&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141408344 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 11/22/2019 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 141408344 141408344 141408344 10.1155/2019/2796971 141408344 ppf: 1 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Measuring Similarity among Protein Sequences Using a New Descriptor. aug: au: Abo-Elkhier, Mervat M. Abd Elwahaab, Marwa A. El Maaty, Moheb I. Abo affil: Department of Engineering Mathematics and Physics, Faculty of Engineering, Mansoura University, Mansoura 35516, Egypt sug: subj: Sequence Analysis Methods Proteins Analysis Research, Medical Technology, Medical Utilization Proteins Physiology Proteins Classification ab: +e comparison of protein sequences according to similarity is a fundamental aspect of today's biomedical research. With the developments of sequencing technologies, a large number of protein sequences increase exponentially in the public databases. Famous sequences' comparison methods are alignment based. +ey generally give excellent results when the sequences under study are closely related and they are time consuming. Herein, a new alignment-free method is introduced. Our technique depends on a new graphical representation and descriptor. +e graphical representation of protein sequence is a simple way to visualize protein sequences. +e descriptor compresses the primary sequence into a single vector composed of only two values. Our approach gives good results with both short and long sequences within a little computation time. It is applied on nine beta globin, nine ND5 (NADH dehydrogenase subunit 5), and 24 spike protein sequences. Correlation and significance analyses are also introduced to compare our similarity/dissimilarity results with others' approaches, results, and sequence homology. pubtype: Academic Journal doctype: equations & formulas review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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