Prevalence of chronic kidney disease in the Lazio region, Italy: a classification algorithm based on health information systems.

Background: Estimating CKD prevalence is difficult. Information on CKD prevalence is rather scanty in Italy and available figures come from surveys in selected geographical areas. Administrative data have been already demonstrated to be an effective tool in estimating the epidemiological burden of d...

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Published in:BMC Nephrology Vol. 21; no. 1; pp. 1 - 11
Main Authors: Marino, Claudia, Ferraro, Pietro Manuel, Bargagli, Matteo, Cascini, Silvia, Agabiti, Nera, Gambaro, Giovanni, Davoli, Marina
Format: Journal Article
Published: BioMed Central 1/28/2020
Online Access:View this record in EBSCOhost
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      dt: 1/28/2020
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        atl: Prevalence of chronic kidney disease in the Lazio region, Italy: a classification algorithm based on health information systems.
      aug:
        au:
          Marino, Claudia
          Ferraro, Pietro Manuel
          Bargagli, Matteo
          Cascini, Silvia
          Agabiti, Nera
          Gambaro, Giovanni
          Davoli, Marina
        affil: Department of Epidemiology Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00147, Roma, Italy
      sug:
        subj:
          Resource Databases
          Algorithms
          Renal Insufficiency, Chronic Epidemiology
          Adolescence
          Middle Age
          Medical Record Linkage
          Young Adult
          Prevalence
          Aged, 80 and Over
          Child, Preschool
          Adult
          Female
          Infant, Newborn
          Health Information Systems
          Child
          Aged
          Infant
          Male
          Italy
          Adolescent: 13-18 years
          Middle Aged: 45-64 years
          Aged, 80 & over
          Child, Preschool: 2-5 years
          Adult: 19-44 years
          Infant, Newborn: birth-1 month
          Child: 6-12 years
          Aged: 65+ years
          Infant: 1-23 months
          Female
          Male
      ab: Background: Estimating CKD prevalence is difficult. Information on CKD prevalence is rather scanty in Italy and available figures come from surveys in selected geographical areas. Administrative data have been already demonstrated to be an effective tool in estimating the epidemiological burden of diseases, however there is limited experience in literature as far as CKD is concerned.Methods: The aim of this study is to develop an algorithm based on regional Health Administrative Databases to identify individuals with CKD and provide estimates of disease prevalence in Lazio Region (Italy); about 5.500.000 inhabitants in 2017. A population-level analysis based on a record-linkage strategy using data from Health Administrative Databases has been applied in Lazio Region. CKD cases were identified between January 1, 2012 and December 31, 2017 using Outpatient Specialist Service Information System, Hospital Discharge Registry, Ticket Exemption Registry and Drug Dispensing Registry. Age-specific and standardized prevalence rates were calculated by gender. CKD cases were classified as higher and lower severity.Results: The algorithm identified 99,457 individuals with CKD (mean age 71 years, 55.8% males). The exclusive contributions of each regional source used were: 35,047 (35.2%) from Outpatient Specialist Service Information System, 27,778 (27.9%) from Hospital Discharge Registry, 4143 (4.2%) from Ticket Exemption Registry and 463 (0.5%) from Drug Dispensing Registry; 5.1% of cases were found in all databases. The standardized prevalence rate at December 31, 2017 was 1.76, 2.06% for males and 1.50% for females. The prevalence increased with age, rising from 0.33% (age 0-18) up to 14.18% (age 85+) among males and from 0.25% up to 8.18% among females. The proportion of CKD individuals with lower severity disease was 78.7% in both genders.Conclusions: The proposed algorithm represents a novel tool to monitor the burden of CKD disease, that can be used by the regional government to guide the development and implementation of evidence-based pathways of care for CKD patients. The high prevalence of people with CKD of lower severity should be carefully considered in order to promote diagnosis and optimal management at early stages.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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