The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults' health-related quality of life: a randomized, double-blind, placebo-controlled clinical trial.
Purpose: The world's older population is growing rapidly and the need to find measures to combat age-associated decline of physical, mental, and cognitive functions and improve their health-related quality of life (HRQOL) is escalating. Biobran/MGN-3, an arabinoxylan rice bran, has been previously r...
| Publicado en: | Quality of Life Research Vol. 29; no. 2; pp. 357 - 368 |
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| Autores principales: | , , , |
| Formato: | research randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Feb2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141513012&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141513012 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: Feb2020 vid: 29 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 141513012 141513012 NLM31489525 141513012 10.1007/s11136-019-02286-7 NLM31489525 141513012 ppf: 357 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults' health-related quality of life: a randomized, double-blind, placebo-controlled clinical trial. aug: au: Elsaid, A. F. Fahmi, R. M. Shaheen, M. Ghoneum, M. affil: Department of Community Medicine and Public Health, Zagazig University, Zagazig, Al Sharqia, Egypt sug: subj: Quality of Life Polysaccharides Therapeutic Use Human Male Female Double-Blind Studies Aged Middle Age Validation Studies Comparative Studies Evaluation Research Multicenter Studies Randomized Controlled Trials Scales Aged: 65+ years Middle Aged: 45-64 years Male Female ab: Purpose: The world's older population is growing rapidly and the need to find measures to combat age-associated decline of physical, mental, and cognitive functions and improve their health-related quality of life (HRQOL) is escalating. Biobran/MGN-3, an arabinoxylan rice bran, has been previously reported to improve the quality of life in cancer patients. The objective of the current study was to examine the effect of a low dose of Biobran/MGN-3 supplementation on the HRQOL in a healthy older adult population.Methods: Sixty apparently healthy subjects, 40 males and 20 females, over 56 years old were recruited and blindly randomized into two group receiving either placebo or Biobran/MGN-3 (250 mg/day for 3 months). Participants did not take any vitamins or medications during the study and their health was closely monitored. HRQOL was assessed at the initiation and termination of the study using the previously validated Arabic version of SF-12v2 questionnaire.Results: For all measured HRQOL domains, there was no statistically significant difference in baseline scores between the two groups. Compared to baseline values and placebo-treated subjects, Biobran/MGN-3 supplementation significantly enhanced the levels of physical and mental component summary scores as well as role-physical, bodily pain, vitality, and social functioning subdomain scores.Conclusion: These results show that Biobran/MGN-3 is a promising psychoneuroimmune modulatory agent that could improve the HRQOL in healthy old adults. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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