Similarities and differences of dietary and other determinants of iodine status in pregnant women from three European birth cohorts.
Purpose: As a component of thyroid hormones, adequate iodine intake is essential during pregnancy for fetal neurodevelopment. Across Europe, iodine deficiency is common in pregnancy, but data are lacking on the predictors of iodine status at this life stage. We, therefore, aimed to explore determina...
| Publicado en: | European Journal of Nutrition Vol. 59; no. 1; pp. 371 - 388 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141544939&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141544939 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Feb2020 vid: 59 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 141544939 141544939 141544939 10.1007/s00394-019-01913-w 141544939 ppf: 371 ppct: 17 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Similarities and differences of dietary and other determinants of iodine status in pregnant women from three European birth cohorts. aug: au: Dineva, Mariana Rayman, Margaret P. Levie, Deborah Guxens, Mònica Peeters, Robin P. Vioque, Jesus González, Llúcia Espada, Mercedes Ibarluzea, Jesús Sunyer, Jordi Korevaar, Tim I. M. Bath, Sarah C. affil: Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, GU2 7XH, Guildford, UK sug: subj: Iodine In Pregnancy Diet In Pregnancy Expectant Mothers Europe Human Pregnancy Female Europe Prospective Studies United Kingdom Spain Netherlands Iodine Urine Creatinine Urine Urinalysis Methods Gestational Age Food Intake In Pregnancy Questionnaires Models, Statistical Multiple Regression Descriptive Statistics Age Factors Dairy Products Shellfish Eggs Cereals Adolescence Adult Adolescent: 13-18 years Adult: 19-44 years Female ab: Purpose: As a component of thyroid hormones, adequate iodine intake is essential during pregnancy for fetal neurodevelopment. Across Europe, iodine deficiency is common in pregnancy, but data are lacking on the predictors of iodine status at this life stage. We, therefore, aimed to explore determinants of iodine status during pregnancy in three European populations of differing iodine status. Methods: Data were from 6566 pregnant women from three prospective population-based birth cohorts from the United Kingdom (ALSPAC, n = 2852), Spain (INMA, n = 1460), and The Netherlands (Generation R, n = 2254). Urinary iodine-to-creatinine ratio (UI/Creat, µg/g) was measured in spot-urine samples in pregnancy (≤ 18-weeks gestation). Maternal dietary intake, categorised by food groups (g/day), was estimated from food-frequency questionnaires (FFQs). Multivariable regression models used dietary variables (energy-adjusted) and maternal characteristics as predictors of iodine status. Results: Median UI/Creat in pregnant women of ALSPAC, INMA, and Generation R was 121, 151, and 210 µg/g, respectively. Maternal age was positively associated with UI/Creat in all cohorts (P < 0.001), while UI/Creat varied by ethnicity only in Generation R (P < 0.05). Of the dietary predictors, intake of milk and dairy products (per 100 g/day) was positively associated with UI/Creat in all cohorts [ALSPAC (B = 3.73, P < 0.0001); INMA (B = 6.92, P = 0.002); Generation R (B = 2.34, P = 0.001)]. Cohort-specific dietary determinants positively associated with UI/Creat included fish and shellfish in ALSPAC and INMA, and eggs and cereal/cereal products in Generation R. Conclusions: The cohort-specific dietary determinants probably reflect not only dietary habits but iodine-fortification policies; hence, public-health interventions to improve iodine intake in pregnancy need to be country-specific. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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