Characteristics of cerebral perfusion and diffusion associated with crossed cerebellar diaschisis after acute ischemic stroke.

Purpose: We aimed to investigate the possible factors associated with the occurrence of crossed cerebellar diaschisis (CCD) at the hyperacute stage of ischemic stroke using whole-brain volume perfusion CT (VPCT) combined with magnetic resonance imaging (MRI).Materials and Methods: We retrospectively...

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Publicado en:Japanese Journal of Radiology Vol. 38; no. 2; pp. 126 - 135
Autores principales: Zhang, Miao, Cao, Yanxiang, Wu, Fang, Zhao, Cheng, Ma, Qingfeng, Li, Kuncheng, Lu, Jie
Formato: Journal Article
Publicado: Springer Nature Feb2020
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Japanese Journal of Radiology
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      dt: Feb2020
      vid: 38
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      pub: Springer Nature
      place: New York, New York
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        NLM31720951
        10.1007/s11604-019-00898-0
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        atl: Characteristics of cerebral perfusion and diffusion associated with crossed cerebellar diaschisis after acute ischemic stroke.
      aug:
        au:
          Zhang, Miao
          Cao, Yanxiang
          Wu, Fang
          Zhao, Cheng
          Ma, Qingfeng
          Li, Kuncheng
          Lu, Jie
        affil: Department of Radiology, Xuanwu Hospital, Capital Medical University, Changchun Street, No. 45, 100053, Beijing, China
      sug:
        subj:
          Stroke Physiopathology
          Stroke
          Cerebral Ischemia
          Cerebrovascular Circulation Physiology
          Cerebral Ischemia Physiopathology
          Cerebral Ischemia Complications
          Magnetic Resonance Imaging Methods
          Retrospective Design
          Female
          Tomography, X-Ray Computed Methods
          Severity of Illness Indices
          Middle Age
          Stroke Complications
          Male
          Brain Blood Supply
          Brain Physiopathology
          Aged
          Aged, 80 and Over
          Brain
          Diagnostic Imaging Methods
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: Purpose: We aimed to investigate the possible factors associated with the occurrence of crossed cerebellar diaschisis (CCD) at the hyperacute stage of ischemic stroke using whole-brain volume perfusion CT (VPCT) combined with magnetic resonance imaging (MRI).Materials and Methods: We retrospectively analyzed 108 patients with ischemic stroke within 6 h of onset. The VPCT findings of the patients showed a unilateral perfusion deficit in the supratentorial territory. Follow-up MRI examinations were performed within 24 h after onset. The effects of the supratentorial cerebral ischemia, the location distribution, the final infarct volume and the apparent diffusion coefficient (ADC) value on the occurrence and severity of CCD were analyzed.Results: Among 108 patients with hyperacute cerebral ischemia, 62 (57.4%) demonstrated a contralateral cerebellar perfusion deficit on the VPCT maps. The occurrence of CCD was related to a reduction in cerebral blood volume (CBV) and prolongation of the mean transit time (MTT). Notably, the decrease in the ADC value in the infarct based on follow-up MRI was closely related to the occurrence and severity of CCD.Conclusion: The occurrence and severity of CCD are related to the degree of low supratentorial perfusion and the decrease in the ADC value of infarct focus.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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