Promoting Memory Consolidation During Sleep: A Meta-Analysis of Targeted Memory Reactivation.
Targeted memory reactivation (TMR) is a methodology employed to manipulate memory processing during sleep. TMR studies have great potential to advance understanding of sleep-based memory consolidation and corresponding neural mechanisms. Research making use of TMR has developed rapidly, with over 70...
| Publicado en: | Psychological Bulletin Vol. 146; no. 3; pp. 218 - 245 |
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| Autores principales: | , , , |
| Formato: | Artículo |
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American Psychological Association
Mar2020
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=141565490&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 141565490 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00332909 PSB jtl: Psychological Bulletin issn: 00332909 maglogo: N pubinfo: dt: Mar2020 vid: 146 iid: 3 pid: 34 pub: American Psychological Association artinfo: ui: 141565490 10.1037/bul0000223 ppf: 218 ppct: 27 formats: tig: atl: Promoting Memory Consolidation During Sleep: A Meta-Analysis of Targeted Memory Reactivation. aug: au: Hu, Xiaoqing Cheng, Larry Y. Chiu, Man Hey Paller, Ken A. affil: Department of Psychology and The State Key Lab of Brain and Cognitive Sciences, The University of Hong Kong, and HKU-Shenzhen Institute of Research and Innovation, Shenzhen, China Department of Psychology, Northwestern University Department of Psychology, The University of Hong Kong Department of Psychology, and Cognitive Neuroscience Program, Northwestern University su: Sleep Memory Explicit memory Rapid eye movement sleep Meta-analysis sug: subj: Sleep Memory Explicit memory Rapid eye movement sleep Meta-analysis keyword: memory consolidation meta-analysis sleep targeted memory reactivation memory consolidation meta-analysis sleep targeted memory reactivation ab: Targeted memory reactivation (TMR) is a methodology employed to manipulate memory processing during sleep. TMR studies have great potential to advance understanding of sleep-based memory consolidation and corresponding neural mechanisms. Research making use of TMR has developed rapidly, with over 70 articles published in the last decade, yet no quantitative analysis exists to evaluate the overall effects. Here we present the first meta-analysis of sleep TMR, compiled from 91 experiments with 212 effect sizes (N = 2,004). Based on multilevel modeling, overall sleep TMR was highly effective (Hedges' g = 0.29, 95% CI [0.21, 0.38]), with a significant effect for two stages of non-rapid-eye-movement (NREM) sleep (Stage NREM 2: Hedges' g = 0.32, 95% CI [0.04, 0.60]; and slow-wave sleep: Hedges' g = 0.27, 95% CI [0.20, 0.35]). In contrast, TMR was not effective during REM sleep nor during wakefulness in the present analyses. Several analysis strategies were used to address the potential relevance of publication bias. Additional analyses showed that TMR improved memory across multiple domains, including declarative memory and skill acquisition. Given that TMR can reinforce many types of memory, it could be useful for various educational and clinical applications. Overall, the present meta-analysis provides substantial support for the notion that TMR can influence memory storage during NREM sleep, and that this method can be useful for understanding neurocognitive mechanisms of memory consolidation. Public Significance Statement: Sensory cues can be used to reactivate associated memories during sleep and thus promote memory consolidation. This meta-analysis shows that targeted memory reactivation during sleep can improve memory performance with a small to moderate effect, and that this effect is most clearly evident when memories are reactivated during Stages 2 and 3 of non-rapid-eye-movement (NREM) sleep. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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