PCOS and Hyperprolactinemia: what do we know in 2019?
Polycystic ovary syndrome (PCOS) and hyperprolactinemia (HPRL) are the two most common etiologies of anovulation in women. Since the 1950s, some authors think that there is a pathophysiological link between PCOS and HPRL. Since then, many authors have speculated about the link between these two endo...
| Publicado en: | Clinical Medicine Insights: Reproductive Health Vol. 13; pp. 1 - 8 |
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| Autores principales: | , , , |
| Formato: | algorithm review tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
9/9/2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141697097&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141697097 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11795581 B3KX jtl: Clinical Medicine Insights: Reproductive Health issn: 11795581 maglogo: Y pubinfo: dt: 9/9/2019 vid: 13 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 141697097 141697097 141697097 10.1177/1179558119871921 141697097 ppf: 1 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: PCOS and Hyperprolactinemia: what do we know in 2019? aug: au: Delcour, Clémence Robin, Geoffroy Young, Jacques Dewailly, Didier affil: Department of Obstetrics and Gynecology, Robert-Debré hospital, AP-HP, Paris, France sug: subj: Polyendocrine Metabolic Ovarian Syndrome Physiopathology Hyperpituitarism Physiopathology Polyendocrine Metabolic Ovarian Syndrome Epidemiology Hyperpituitarism Epidemiology Polyendocrine Metabolic Ovarian Syndrome Diagnosis Hyperpituitarism Diagnosis Women's Health Anovulation Physiopathology Prolactin Blood ab: Polycystic ovary syndrome (PCOS) and hyperprolactinemia (HPRL) are the two most common etiologies of anovulation in women. Since the 1950s, some authors think that there is a pathophysiological link between PCOS and HPRL. Since then, many authors have speculated about the link between these two endocrine entities, but no hypothesis proposed so far could ever be confirmed. Furthermore, PCOS and HPRL are frequent endocrine diseases and a fortuitous association cannot be excluded. The evolution of knowledge about PCOS and HPRL shows that studies conducted before the 2000s are obsolete given current knowledge. Indeed, most of the studies were conducted before consensual diagnosis criteria of PCOS and included small numbers of patients. In addition, the investigation of HPRL in these studies relied on obsolete methods and did not look for the presence of macroprolactinemia. It is therefore possible that HPRL that has been attributed to PCOS corresponded in fact to macroprolactinemia or to pituitary microadenomas of small sizes that could not be detected with the imaging methods of the time. Recent studies that have conducted a rigorous etiological investigation show that HPRL found in PCOS correspond either to non-permanent increase of prolactin levels, to macroprolactinemia or to other etiologies. None of this recent study found HPRL related to PCOS in these patients. Thus, the link between PCOS and HPRL seems to be more of a myth than a well-established medical reality and we believe that the discovery of an HPRL in a PCOS patient needs a standard etiological investigation of HPRL. pubtype: Academic Journal doctype: algorithm review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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