Detecting Congestive Heart Failure by Extracting Multimodal Features and Employing Machine Learning Techniques.

The adaptability of heart to external and internal stimuli is reflected by the heart rate variability (HRV). Reduced HRV can be a predictor of negative cardiovascular outcomes. Based on the nonlinear, nonstationary, and highly complex dynamics of the controlling mechanism of the cardiovascular syste...

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Publicado en:BioMed Research International pp. 1 - 20
Autores principales: Hussain, Lal, Awan, Imtiaz Ahmed, Aziz, Wajid, Saeed, Sharjil, Ali, Amjad, Zeeshan, Farukh, Kwak, Kyung Sup
Formato: equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 2/18/2020
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
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      dt: 2/18/2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2020/4281243
        141922434
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        atl: Detecting Congestive Heart Failure by Extracting Multimodal Features and Employing Machine Learning Techniques.
      aug:
        au:
          Hussain, Lal
          Awan, Imtiaz Ahmed
          Aziz, Wajid
          Saeed, Sharjil
          Ali, Amjad
          Zeeshan, Farukh
          Kwak, Kyung Sup
        affil: Department of Computer Science & IT, The University of Azad Jammu and Kashmir, City Campus, 13100 Muzaffarabad, Azad Kashmir, Pakistan
      sug:
        subj:
          Automation
          Machine Learning
          Heart Failure Diagnosis
          Human
          Models, Statistical
          Decision Trees
          Sensitivity and Specificity
          Predictive Value of Tests
          ROC Curve
          Confidence Intervals
      ab: The adaptability of heart to external and internal stimuli is reflected by the heart rate variability (HRV). Reduced HRV can be a predictor of negative cardiovascular outcomes. Based on the nonlinear, nonstationary, and highly complex dynamics of the controlling mechanism of the cardiovascular system, linear HRV measures have limited capability to accurately analyze the underlying dynamics. In this study, we propose an automated system to analyze HRV signals by extracting multimodal features to capture temporal, spectral, and complex dynamics. Robust machine learning techniques, such as support vector machine (SVM) with its kernel (linear, Gaussian, radial base function, and polynomial), decision tree (DT), k-nearest neighbor (KNN), and ensemble classifiers, were employed to evaluate the detection performance. Performance was evaluated in terms of specificity, sensitivity, positive predictive value (PPV), negative predictive value (NPV), and area under the receiver operating characteristic curve (AUC). The highest performance was obtained using SVM linear kernel (TA = 93.1%, AUC = 0.97, 95% CI [lower bound = 0.04, upper bound = 0.89]), followed by ensemble subspace discriminant (TA = 91.4%, AUC = 0.96, 95% CI [lower bound 0.07, upper bound = 0.81]) and SVM medium Gaussian kernel (TA = 90.5%, AUC = 0.95, 95% CI [lower bound = 0.07, upper bound = 0.86]). The results reveal that the proposed approach can provide an effective and computationally efficient tool for automatic detection of congestive heart failure patients.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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