Leveraging Integrated Continuous Manufacturing to Address Critical Issues in the U.S. Military.

There is a tremendous opportunity to modernize the pharmaceutical manufacturing industry-relinquishing outdated machines that have been used for decades, and replacing them with state-of-the-art equipment that reflect more contemporary advanced technologies. This article describes how the implementa...

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Publicado en:Military Medicine Vol. 185; pp. 656 - 663
Autores principales: Takizawa, Bayan Teisho, Born, Stephen Christopher, Mascia, Salvatore
Formato: Journal Article
Publicado: Oxford University Press / USA 2020 Supplement
Acceso en línea:Ver este registro en EBSCOhost
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          Takizawa, Bayan Teisho
          Born, Stephen Christopher
          Mascia, Salvatore
        affil: CONTINUUS Pharmaceuticals, Inc., 25-R Olympia Avenue, Woburn MA 01801
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        subj:
          Military Personnel Statistics and Numerical Data
          Industry Trends
          Industry Methods
          Cooperative Behavior
          United States
          Ferrans and Powers Quality of Life Index
          Impact of Events Scale
      ab: There is a tremendous opportunity to modernize the pharmaceutical manufacturing industry-relinquishing outdated machines that have been used for decades, and replacing them with state-of-the-art equipment that reflect more contemporary advanced technologies. This article describes how the implementation of continuous manufacturing, replacing outdated batch systems, can positively impact our health care sector. Important benefits will include the creation of advanced pharmaceutical manufacturing jobs in the United States, the establishment of capabilities and capacity to quickly produce drugs critical to U.S. citizens, the reduction of health care costs through more efficient manufacturing, and access to better quality drugs through more sophisticated and reliable production processes. Furthermore, the application of continuous manufacturing will enable the U.S. Government, in partnership with pharmaceutical companies, to address current issues such as drug shortages, national emergencies (eg, natural disasters or chemical, biological, radiological, or nuclear threats), the Strategic National Stockpile (ie, improving response time and reducing maintenance costs), and the delivery of critical drugs to distant geographies (eg, forward military bases). The article also provides a detailed example of a critical aspect of continuous manufacturing: the ability to overcome technical challenges encountered by batch technologies.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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