Utilization of 19F MRI for Identification of Iraq-Afghanistan War Lung Injury.
Introduction: There is mounting evidence of respiratory problems related to military service in the Middle East in the past two decades due to environmental exposures during deployment (eg, sand storms and burn pits). This pilot study tests the hypothesis that regional lung function in subjects with...
| Publicado en: | Military Medicine Vol. 185; pp. 50 - 57 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
2020 Supplement
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141923089&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141923089 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00264075 4DV jtl: Military Medicine issn: 00264075 maglogo: N pubinfo: dt: 2020 Supplement vid: 185 pid: 622 pub: Oxford University Press / USA artinfo: ui: 141923089 141923089 NLM32074359 141923089 10.1093/milmed/usz284 NLM32074359 141923089 ppf: 50 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Utilization of 19F MRI for Identification of Iraq-Afghanistan War Lung Injury. aug: au: Mammarappallil, Joseph G Shofer, Scott Carraway, Martha S Tucker, Jesse Womack, Samantha Ainslie, Maureen Charles, H Cecil affil: Department of Radiology, Duke University School of Medicine, 2301 Erwin Road, Durham, NC 27705 sug: subj: Magnetic Resonance Imaging Methods Lung Injury Data Collection Adult Oxygen Therapy Methods Pilot Studies Magnetic Resonance Imaging Equipment and Supplies Male United States Human Magnetic Resonance Imaging Statistics and Numerical Data Female Middle Age Validation Studies Comparative Studies Evaluation Research Multicenter Studies Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Introduction: There is mounting evidence of respiratory problems related to military service in the Middle East in the past two decades due to environmental exposures during deployment (eg, sand storms and burn pits). This pilot study tests the hypothesis that regional lung function in subjects with prior deployment in Iraq and/or Afghanistan with suspected War Lung Injury (WLI) would be worse than subjects with normal lung function.Materials and Methods: Five subjects meeting the inclusion and exclusion criteria were recruited for this pilot study. All subjects underwent spirometry, high-resolution chest computed tomography imaging, and 19F MRI.Results: While the WLI subjects had normal pulmonary function tests and normal high-resolution chest computed tomography evaluations, their regional lung function from 19F MRI was abnormal with compartments with poor function showing slower filling time constants for ventilation. The scans of suspected WLI subjects show higher fractional lung volume with slow filling compartments similar to patients with chronic obstructive pulmonary disease in contrast to normal subjects.Conclusions: This is consistent with our premise that WLI results in abnormal lung function and reflects small airways dysfunction and suggests that we may be able to provide a more sensitive tool for evaluation of WLI suspected cases. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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